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Commitment to cell division at the end of G1 phase, termed Start in the budding yeast Saccharomyces cerevisiae, is strongly influenced by nutrient availability. To identify newdominant activators of Start that might operate under different nutrient conditions, we screened a genome-wide ORF overexpr...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-08-25 | PXD018681 | Pride
A significant fraction of the Saccharomyces cerevisiae genome is transcribed periodically during the cell division cycle, indicating that properly timed gene expression is important for regulating cell-cycle events. Genomic analyses of the localization and expression dynamics of transcription factor...
A mathematical model of regulation of the G1-S transition of the mammalian cell cycle has been formulated to organize available experimental molecular-level information in a systematic quantitative framework and to evaluate the ability of this manifestation of current knowledge to calculate correctl...
2020-05-07 | MODEL2005070001 | BioModels
Single cell RNA sequencing (scRNA-seq) of GM12878 cells upon G1/S blocker or control (DMSO) and Sendai virus infection.
ORGANISM(S): Homo sapiens 
ATAC-seq of human GM12878 cells to detect chromatin accessibility changes upon G1/S arrest (aphidicolin treated samples) and /or infection (Sendai virus) compared to control.
ORGANISM(S): Homo sapiens 
Human B lympoblastoid cells, GM12878 and human T cells, JURKAT, were treated with aphidicolin (to arrest cells at G1/S boundary) for 24h, the last 12h with the Sendai virus. The experiment was performed in three biological replicates. Gene expression changes upon aphidicolin and or infection betwee...
ORGANISM(S): Homo sapiens 
In this report, we examine transcripts on a genome-wide level between the synchronized cell cycles of hESCs and hESC-derived endoderm cells. We found 10347, 10299 and 10362 genes expressed in the G1, G1/S, and S phase of hESCs, respectively; 10333, 10227 and 10215 genes expressed at the G1, G1/S and...
ORGANISM(S): Homo sapiens 
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