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UnknownStress Hyperglycemia Ratio and Adverse Outcomes in Acute Mild Ischemic Stroke or High-Risk Transient Ischemic Attack: A Secondary Analysis of the INSPIRES Trial.
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S-EPMC12829502 | biostudies-literature
ProteomicsPhosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway
In this study, we found that CB inhibited ICC cell proliferation and promoted cell apoptosis. By using phosphoproteomics, we found significant changes in the proteome and phosphorylome associated with DNA damage and apoptosis in response to CB treatment. Further investigations demonstrated that CB i...
ORGANISM(S): Homo Sapiens 
2022-06-20 | PXD034717 |
ProteomicsCN-CHPP 2015 Testis Project - Tissue-Based Proteogenomics Reveals that Human Testis Endows Plentiful Missing Proteins
The testis tissue-based trans-omics was a feasible approach to find more missing proteins (MPs) because it was reported higher gene expression found in testis tissues. Three testis tissues and two protein separation strategies were selected to quantitatively evaluate gene expression abundance at the...
ORGANISM(S): Homo sapiens (Human) 
2015-11-03 | PXD002179 | Pride
Transcriptome Testis Chromosome-centric human proteome project Proteome Missing proteins 
ProteomicsIdentification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
Identification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
ORGANISM(S): Homo Sapiens 
2023-07-13 | PXD043745 |
ProteomicsSynthetic yeast genome project
The experiment aimed to study the proteome variation in a yeast strain (YS031), which chromosome II was artificially synthezied, compared with the wild type strain (BY4741). Proteins were extracted from the yeast cells and digested with trypsin. The peptides were label with iTRAQ, separated with 2D ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-10-27 | PXD003435 | Pride
Saccharomyces cerevisiae Itraq Lc-ms/ms 
ProteomicsProteomics analysis of three tea cultivars
To decipher phenotypic differences in flavonoid metabolism and the abundance of UGT enzymes involved in flavonol glycoside biosynthesis, an integrated proteomics and metabolomics analysis was conducted on three tea cultivars (Camellia sinensis), namely Jinfenghuang, Fuyun 6 and Bantianyao.
ORGANISM(S): Camellia Sinensis 
2024-01-30 | PXD048997 |
ProteomicsYKT6 is essential for male fertility by promoting meiosis progression through vesicular transport regulation during spermatogenesis of mice
The tetraploid spermatocytes of postnatal days (PD) 16 Ykt6-Ctrl and Ykt6-cKO mice obtained by fluorescence-activated cell sorting were subjected to proteomics analysis. After three rinses with phosphate-buffered saline (PBS), the samples were gathered into tubes containing lysis buffer, flash froze...
ORGANISM(S): Mus Musculus 
2025-04-22 | PXD063213 |
ProteomicsAn essential maternal PADI6-UHRF1-UBE2D (MPU) complex regulates protein ubiquitination during oocyte maturation and embryogenesis
100 WT or Padi6Null MII oocytes for MS samples from three independent experiments and IP samples in 500 MII oocytes from one experiment were used for Mass spectrometry analysis.
ORGANISM(S): Mus Musculus 
2025-01-25 | PXD060230 |
ProteomicsLow-input redoxomics facilitates global identification of metabolic regulators of oxidative stress in the gut
we developed a low-input and user-friendly pipeline for the simultaneous profiling of five distinct Cys states with regional resolution in the gut of monkeys, including free SH, total Cys oxidation (Sto), sulfenic acid (SOH), S-nitrosylation (SNO), and S-glutathionylation (SSG), shedding light on re...
ORGANISM(S): Macaca Fascicularis Fascicularis Homo Sapiens Mus Musculus 
2024-12-16 | PXD053818 |
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