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TranscriptomicsAstrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis
Double transgenic mice with hepatocyte-specific expression of AEG-1 and c-Myc show aggressive HCC compared to single transgenics. Gene expression was analyzed to understand the molecular mechanism by which AEG-1 and c-Myc cooperate to promote hepatocarcinogenesis. Livers were collected from naïve ad...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-61875 | biostudies-arrayexpress
TranscriptomicsRetroviral insertional mutagenesis screen in a C/EBPalpha proliferative genetic background
The CCAAT enhancer binding protein alpha (C/EBPalpha) transcription factor plays a key role in the regulation of growth and differentiation of the granulocytic lineage in the hematopoietic system and CEBPA (encoding C/EBPalpha) is often mutated or deregulated in AML patients. Consistently, mice lack...
ORGANISM(S): Mus musculus 
2008-05-31 | E-GEOD-8032 | biostudies-arrayexpress
UnknownStereoselective Synthesis of Nojirimycin α-C-Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C-Biantennary Glycomimetics.
Not available
S-EPMC9260894 | biostudies-literature
GenomicsExpression data from betalains treated C. elegans
Expression data from betalains treated C. elegans
PRJNA555856 | ENA
GenomicsExpression data from baicalein treated C. elegans
Expression data from baicalein treated C. elegans
PRJNA556638 | ENA
GenomicsExpression data from food colorants treated C. elegans
Expression data from food colorants treated C. elegans
PRJNA601110 | ENA
TranscriptomicsCGH Analysis of C. jejuni isolates
We performed microarray CGH analysis of 104 neuropathogenic and enteritis only stains of C. jejuni. Keywords: Individual hybridizations, CGH We measured signal intensity for tester strain versus control strain Cj NCTC 11168 for 104 isolates of C. jejuni.
ORGANISM(S): Campylobacter jejuni 
2007-09-30 | E-GEOD-3579 | biostudies-arrayexpress
ProteomicsProteome changes as consequence of altered c-di-GMP metabolism in BCG
Pellicles, a type of biofilm, have gathered a renewed interest in the field of tuberculosis as a structure that mimics some characteristics occurring during M. tuberculosis infection, such as antibiotic recalcitrance and chronicity of infection. In other bacteria, it has been well documented that th...
ORGANISM(S): Mycobacterium bovis BCG str. Pasteur 1173P2 
2018-03-21 | PXD005894 | Pride
C-di-gmp Mycobacteria Pellicle Proteome 
TranscriptomicsDeep sequencing of C. elegans microRNAs under starvation conditions
In nature, animals often face feast or famine conditions. We aimed to identify the miRNAs of Caenorhabditis elegans that changed their expression under starvation conditions in stage L4 larvae. Our results highlight 14 miRNAs that show differential expression in starved versus well-fed larvae. In pa...
ORGANISM(S): Caenorhabditis elegans 
2016-01-27 | E-GEOD-67711 | biostudies-arrayexpress
ProteomicsCdh1 Proteomic Analysis - A Synthetic Lethal Interaction between APC/C and Topoisomerase Poisons Uncovered by Proteomic Screens
The Anaphase-promoting complex/cyclosome (APC/C) cofactor Cdh1 modulates proliferation and cell cycle exit by targeting multiple cell cycle regulators for ubiquitin-dependent degradation. Lack of Cdh1 results in structural and numerical chromosome aberrations, a hallmark of genomic instability, alth...
ORGANISM(S): Mus musculus (Mouse) 
2014-02-20 | PXD000511 | Pride
Ubiquitination Cdh1 Silac Mouse Apc/c Cell cycle Itraq 
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