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UnknownUpregulation of Ying Yang 1 (YY1) suppresses esophageal squamous cell carcinoma development through heme oxygenase-1.
Not available
S-EPMC7656543 | biostudies-literature
ProteomicsHuman HEK293T and Pig cardiac top-down proteomes from Bruker maXis II
These data, derived from PXD019368 (PMID 33231430) and PXD010825 (PMID 30988469) represent a test of deconvolution algorithms for top-down proteomics experiments on the Bruker maXis II Q-TOF. Three LC-MS/MS experiments are available from pig cardiac tissue in both raw .d directories and in deconvol...
ORGANISM(S): Sus Scrofa (ncbitaxon:9823) Homo Sapiens (ncbitaxon:9606) 
2022-04-13 | MSV000089252 | MassIVE
ProteomicsNitric oxide modulates Saccharomyces cerevisiae biofilm formation though regulating the transmembrane protein CTR1 by activating its transcriptional factor MAC1.
Biofilms with immobilized cells in industrial fermentation are beneficial. Encased in extracellular polymeric substance, cells forming biofilms are regulated by various factors. Nitric oxide (NO), as a signaling molecule, recognized as quorum sensing molecule regulating microbe biofilm formation. Re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-12 | PXD010751 | Pride
Transcription factor mac1 Nitric oxide Saccharomyces cerevisiae Biofilm 
ProteomicsUltrafast and Reproducible Proteomics from Small amounts of Heart Tissue Enabled by Azo and timsTOF Pro
Data for the manuscript "Ultrafast and Reproducible Proteomics from Small amounts of Heart Tissue Enabled by Azo and timsTOF Pro".
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-21 | MSV000087476 | MassIVE
UnknownCore pluripotency factors promote glycolysis of human embryonic stem cells by activating GLUT1 enhancer.
Not available
S-EPMC6711954 | biostudies-literature
ProteomicsLactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs
top down and bottom up proteomics files for Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-05-05 | MSV000091869 | MassIVE
ProteomicsTop-down Proteomics of Large Proteins Up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy
Mass spectrometry (MS)-based top-down proteomics is a powerful method for the comprehensive analysis of proteoforms that arise from genetic variations and post-translational modifications (PTMs). However, top-down MS analysis of high molecular weight (MW) proteins remains challenging mainly due to t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-11-29 | MSV000080365 | MassIVE
UnknownDietary Polyphenol Intake and Risk of Hypertension: An 18-y Nationwide Cohort Study in China.
Not available
S-EPMC10447504 | biostudies-literature
ProteomicsTop-down murine MMTV-PyMT proteoform landscape
We developed a top-down proteomic approach to characterize late-stage, primary tumor tissues harvested from MMTV-PyVT mice. This methodology allowed us to expand the coverage for high MW proteoforms using a murine model of breast cancer.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD059164 | Pride
Post-translational modifications 2d-sec-rpc-ms High molecular weight proetoforms Breast cancer Proteoform Mmtv-pymt tumors 
ProteomicsGlobal bottom-up analysis of wild type and RBM20 knock out rat hearts by LC-TIMS-MSMS
Dilated cardiomyopathy (DCM) is a major risk factor for developing heart failure and is often associated with an increased risk for life-threatening arrhythmia. Although numerous causal genes for DCM have been identified, RNA binding motif 20 (RBM20) remains one of the few splicing factors that, whe...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-05-12 | PXD033429 | Pride
Rat Rbm20 Heart Timstof pro 
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