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UnknownSubcutaneous implantable cardioverter defibrillators in patients with left ventricular assist devices: case report and comprehensive review.
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S-EPMC6601396 | biostudies-literature
ProteomicsR. etli CFN42 proteomes showed isoenzymes in free-living and symbiosis with a different transcriptional regulation inferred from a transcriptional regulatory network
Abstract A comparative proteomic study at 6 h of growth in minimal medium (MM) and bacteroids at 18 days of symbiosis of Rhizobium etli CFN42 with the Phaseolus vulgaris leguminous plant was performed. A gene ontology classification of proteins in MM and bacteroid, showed 31 and 10 pathways with hig...
ORGANISM(S): Rhizobium etli CFN 42 
2022-09-27 | PXD035204 | Pride
Lc-ms/ms Transcriptional Network Rhizobium Regulation 
ProteomicsIntegrated lysine acetylation stoichiometry and proteomics analysis in human cells
Lysine acetylation is a widespread posttranslational modification that targets a large number of biological pathways. Recent studies reveal that lysine acetylation sites exhibit mainly low stoichiometry. Here we explored three sample preparation methods, the use of detergents for the chemical acetyl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-09 | MSV000081704 | MassIVE
ProteomicsIntegrated lysine acetylation stoichiometry and proteomics analysis in human cells
Lysine acetylation is a widespread posttranslational modification that targets a large number of biological pathways. Recent studies reveal that lysine acetylation sites exhibit mainly low stoichiometry. Here we explored three sample preparation methods, the use of detergents for the chemical acetyl...
ORGANISM(S): Homo sapiens (Human) 
2017-09-12 | PXD005903 | Pride
Deacetylase inhibitor Sirt1 Cancer cells Lysine acetylation Stoichiometry Proteomics 
TranscriptomicsTranscriptomic impact of AWR5 effector expression in S. cerevisiae
The type III effector (T3E) AWR5 from the phytopathogen Ralstonia solanacearum causes disease in many plants relevant in agriculture. Heterologous expression in yeast of AWR5 from an integrated tetO promoter caused strong growth inhibition. In this series of experiments we investigate the possible c...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-31 | E-GEOD-70202 | biostudies-arrayexpress
TranscriptomicsExpression profile of A459 cells upon LKB1 expression
The purpose of the experiment is to study the expression profiles variations upon the expression of the wild type isoform of LKB1 (STK11) in human lung carcinoma A459 cells. These cells are KRAS mutated and null for STK11. Cells were previously infected with the lentiviral construct pLenti-rtTA2-IRE...
ORGANISM(S): Homo sapiens 
2020-06-11 | E-MTAB-8863 | biostudies-arrayexpress
ProteomicsDynamics of Mitochondrial Proteome and Acetylome in Glioblastoma Cells with Contrasting Metabolic Phenotypes
The dysregulated energy metabolism of glioblastoma cells is a critical factor in tumor development and progression. Lysine acetylation, regulated by the mitochondrial enzyme SIRT3, is known to play a key role in the metabolic phenotype of glioblastoma. To better understand how SIRT3 regulates mitoch...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD045197 | Pride
Metabolism Lysine acetylation Sirt3 Glioblastoma Mitochondria 
ProteomicsSecretome cervical cancer LC-MS/MS
The molecular processes and proteomic markers leading to tumour development (TD) in cervical cancer (CC) are either unknown or only partially understood. TD affects metabolic and regulatory mechanisms that can be identified as proteomic changes. To identify which proteins are differentially expresse...
ORGANISM(S): Homo sapiens (Human) 
2018-05-23 | PXD005466 | Pride
Hsp70 Secreted proteins Siha Hsp60 Hela 
ProteomicsA proteomic study of the dual oncogenic and tumor- suppressive roles of SIRT3 in lung and breast cancer cell lines
The mitochondria play a crucial role in metabolism and energy production by generating adenosine triphosphate (ATP) through oxidative phosphorylation. Additionally, they are involved in maintaining intracellular calcium levels, facilitate nuclear communication, detoxify reactive oxygen species (ROS)...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD063181 | Pride
Mitochondria  cancer  post-translational modification  acetylation  sirtuin  metabolism  oxidative phosphorylation 
ProteomicsTMEM160 Promotes Tumor Growth in Lung Adenocarcinoma and Cervical Adenocarcinoma Cell Lines
This dataset corresponds to the proteomic characterization of the TMEM160 interactome in A549 cells using co-immunoprecipitation (Co-IP) followed by data-independent acquisition mass spectrometry (DIA-MS). TMEM160 was immunoprecipitated using an anti-TMEM160 antibody, and interacting proteins were i...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD071042 | Pride
C-hpp  tmem160  non-small cell lung cancer  cervical cancer  tumor growth  nuclear localization dia-nn  dia proteomics  co-ip proteomics  a549 cells 
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