Early-onset Parkinson's disease can be caused by mutations in the gene PARK7. Many functions have been proposed for PARK7, but in vivo evidence is largely lacking or conflicting with enzymological data. Here, we provide unequivocal evidence that PARK7 and its orthologues can prevent damage of protei...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Oryctolagus cuniculus (Rabbit) Saccharomyces cerevisiae (Baker's yeast) Drosophila melanogaster (Fruit fly)