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UnknownThe Gene Ontology (GO) database and informatics resource.
Not available
S-EPMC308770 | biostudies-literature
TranscriptomicssiRNA ELK1 depletion and EGF stimulation
ELK1 is a well-known target of the ERK branch (EGF-responsive) of the MAP kinase pathway. This transcription profiling experiment studied the effects of ELK1 depletion by siRNA and subsequent EGF stimulation.
ORGANISM(S): Homo sapiens 
2012-07-20 | E-MEXP-3407 | biostudies-arrayexpress
TranscriptomicsCharacterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing
We report on the characterization of lipogenic tissue transcriptional networks that support physiological responses of obese rats to a lipid-lowering bioactive food compound, R-a-lipoic acid (LA). Nine-week old male ZDF (fa/fa) rats were fed a chow diet supplemented with 3 g LA per kg diet or pair f...
ORGANISM(S): Rattus norvegicus 
2014-01-08 | E-GEOD-50424 | biostudies-arrayexpress
ProteomicsComparative proteomic analysis of Plasmodium falciparum parasites with and without the prenol kinase-encoding gene (knockout parasites)
The methylerythritol 4-phosphate (MEP) pathway, essential for producing isoprenoids in Plasmodium parasites. The key isoprenoids produced by the MEP pathway are farnesyl and geranylgeranyl pyrophosphates (FPP and GGPP), vital for protein isoprenylation, ubiquinone, and dolichol biosynthesis. In vitr...
ORGANISM(S): Plasmodium falciparum NF54 
2026-09-16 | PXD059094 | Pride
Geranylgeraniol Knockout Malaria Isoprenoid metabolism Farnesol Plasmodium falciparum Prenol kinase 
ProteomicsGené organ engagement in lipid metabolism revealed by a combined transcriptomic and proteomic approach
Gené organ (GO) is an exclusive apparatus of female ticks that secretes a protective wax coat onto the egg surface. This wax coat makes eggs more viable in the environment due to its waterproof, stickiness and antimicrobial proprieties. In this work, a combined transcriptomic and proteomic approach ...
ORGANISM(S): Rhipicephalus microplus 
2022-03-01 | PXD011223 | Pride
Transcriptome Gené organ Lipid gland Tick Egg wax Proteome 
UnknownMeasurement properties of the Timed Up & Go test in patients with COPD.
Not available
S-EPMC5734421 | biostudies-literature
UnknownTargeted activation of human ether-a-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant.
Not available
S-EPMC10676460 | biostudies-literature
UnknownChloroplast genomes of Simarouba Aubl., molecular evolution and comparative analyses within Sapindales.
Not available
S-EPMC11393331 | biostudies-literature
UnknownEnhancing the R-ISS classification of newly diagnosed multiple myeloma by quantifying circulating clonal plasma cells.
Not available
S-EPMC7724649 | biostudies-literature
TranscriptomicsGene expression patterns in Schistosoma mansoni larvae and eggs
Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts. The infective schistosome cercaria develops from an undifferentiated germ ball within the daughter sporocyst in the molluscan host, during which considerable morphological develo...
ORGANISM(S): Schistosoma mansoni 
2010-05-29 | E-GEOD-22037 | biostudies-arrayexpress
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