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TranscriptomicsDistinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway
Medulloblastoma is a malignant brain tumor that occurs predominantly in children. Current risk stratification based on the clinical parameters is inadequate for accurate prognostication. In order to get a better understanding of medulloblastoma biology, miRNA profiling of medulloblastomas was carrie...
ORGANISM(S): Homo sapiens 
2012-10-27 | E-GEOD-41842 | biostudies-arrayexpress
UnknownInsight into ferromagnetic interactions in CuII-LnIII dimers with a compartmental ligand.
Not available
S-EPMC10845014 | biostudies-literature
ProteomicsCharacterization of detergent insoluble proteome in chronic traumatic encephalopathy
Proteomic sequencing of postmortem human brain can identify dysfunctional proteins that contribute to neurodegenerative disorders like Alzheimer’s disease and frontotemporal dementia. Similar studies in chronic traumatic encephalopathy are limited, but may provide important new insights into this di...
ORGANISM(S): Homo sapiens (Human) 
2017-11-27 | PXD007694 | Pride
Proteostasis Ad Detergent insoluble proteome Human brain cte Alzheimer's disease Dementia pugilistica 
UnknownSelective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children.
Not available
S-EPMC9640272 | biostudies-literature
TranscriptomicsDiscovery of novel imprinted genes by transcriptional analysis of parthenogenetic embryonic stem cells
Parthenogenetic embryonic stem cells (PESCs) may have future utility in cell replacement therapies. We examined genome-wide mRNA expression profiles of monkey PESCs relative to ESCs derived from fertilized embryos. Several known paternally-imprinted genes were in the highly down-regulated group in P...
ORGANISM(S): Macaca mulatta 
2010-07-07 | E-GEOD-17964 | biostudies-arrayexpress
UnknownDynamical facilitation governs glassy dynamics in suspensions of colloidal ellipsoids.
Not available
S-EPMC4217396 | biostudies-literature
UnknownMigration alters oscillatory dynamics and promotes survival in connected bacterial populations.
Not available
S-EPMC6288160 | biostudies-literature
UnknownChemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels.
Not available
S-EPMC6104687 | biostudies-literature
ProteomicsTargeting G1–S Checkpoint–Compromised Cancers with Cyclin A/B RxL Inhibitors
Cancer cell proliferation requires precise control of E2F1 activity; excess activity promotes apoptosis. Here, we developed cell-permeable and bioavailable macrocycles that selectively kill small cell lung cancer (SCLC) cells with inherent high E2F1 activity by blocking RxL-mediated interactions of ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-30 | PXD055112 | Pride
Macrocycle Cyclin a E2f Cyclin b Cy/rxl motif Cdk2 Sac Synthetic lethality 
UnknownClassical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.
Not available
S-EPMC5584859 | biostudies-literature
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