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MetabolomicsOral-gut microbiome and plasma metabolome reveal incremental restratification of coronary artery disease from the clinical gray zone
Clinical prediction models have been widely applied for risk stratification of coronary artery disease (CAD), yet approximately 20% to 40% of screened individuals fall into the intermediate-risk interval and face a decision gap. Here, we adopted a two-stage validation design. In the first stage, a c...
2026-08-31 | MTBLS15425 | MetaboLights
TranscriptomicsMicroarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer’s disease
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that threatens to reach epidemic proportions as our population ages. Although much research has examined molecular pathways associated with AD, relatively few studies have focused on critical early stages. Our prior microarray stud...
ORGANISM(S): Homo sapiens 
2011-07-31 | E-GEOD-28146 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human post mortem spinal cord grey matter from sporadic and familial ALS patients vs controls to identify amyotrophic lateral sclerosis (ALS) associated genes
Identification of amyotrophic lateral sclerosis (ALS) associated genes. Post mortem spinal cord grey matter from sporadic and familial ALS patients compared with controls.
ORGANISM(S): Homo sapiens 
2007-09-26 | E-GEOD-833 | biostudies-arrayexpress
MetabolomicsDIVA Metabolomics: Differentiating Vaccination Status Following Viral Challenge Using Metabolomic Profiles
This study employed metabolomic profiling technologies, to identify metabolites (small molecules) in blood which are found at different levels in vaccinated compared to non-vaccinated animals exposed to virus.
2018-07-13 | MTBLS456 | MetaboLights
TranscriptomicsAspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
Transcriptional profiling of A. nidulans comparing starvation for 0 (reference), 12 and 24 h. The main objective was to identify genes specifically regulated during starvation by atmA and xprG. The results of the experiment were further validated by real-time PCR. Experimental procedure: Three A. ni...
ORGANISM(S): Emericella nidulans 
2012-12-07 | E-GEOD-42732 | biostudies-arrayexpress
ProteomicsNeutrophil specific granule and NETosis defect in Gray Platelet Syndrome
Gray Platelet Syndrome (GPS) is an autosomal recessive bleeding disorder characterized by a lack of α-granules in platelets and progressive myelofibrosis. Rare loss of function variants in NBEAL2, a member of the family of BEACH genes, are causal of GPS. The gene is involved in fusion, fission and t...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD017784 | Pride
Neutrophil Gray platelet syndrome 
TranscriptomicsTBI induced intestinal tissue damage
Tissue damage precedes GvHD and the events leading up to this inflammatory disease are not well understood. To identify cell populations that may invade the intestinal tract after total body irradiation (TBI), we performed a microarray based gene expression analysis of the intestinal tract isolated ...
ORGANISM(S): Mus musculus 
2014-04-28 | E-MTAB-1566 | biostudies-arrayexpress
ProteomicsNovel manifestations of immune dysregulation and granule defects in gray platelet syndrome.
Comparitive proteomics analyses of different cell types of blood i.e. platelets, neutrophils, monocytes and CD4 derived from the Gray platelet syndrome patients and their respective controls using TMT10plex reagents.
ORGANISM(S): Homo sapiens (Human) 
2020-07-23 | PXD016366 | Pride
Secretion Bleeding Neutrophils Immunity Platelets Vesicles 
GenomicsAspergillus nidulans
Aspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
PRJNA183165 | ENA
TranscriptomicsExon profiling of human Gray (LBNL) breast cancer cell lines
Exon array profiling of Gray (LBNL) breast cancer cell lines
ORGANISM(S): Homo sapiens 
2010-12-01 | E-MTAB-181 | biostudies-arrayexpress
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