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TranscriptomicsTranscription profiling of rat nasal respiratory and olfactory epithelium
The nasal epithelium is an important target site for chemically-induced toxicity and carcinogenicity. Human epidemiological investigations and experimental laboratory animal studies show that the nasal olfactory epithelium is selectively damaged by inhalation exposure to several chemicals, includin...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5019 | biostudies-arrayexpress
UnknownPrescribing Data in General Practice Demonstration (PDGPD) project--a cluster randomised controlled trial of a quality improvement intervention to achieve better prescribing for chronic heart failure and hypertension.
Not available
S-EPMC3515472 | biostudies-literature
OtherQuantification of Extracellular Matrix Proteins from a Rat Lung Scaffold to Provide a Molecular Readout for Tissue Engineering.
Data from ProteomeXchange, PXD ID: PXD001213. File: 20121108_Native_Frac3_Lung01_Run03.mzml. Published as part of . From the Abstract: {{i}} ... To support organ engineering efforts, we developed a targeted proteomics method to extract and quantify extracellular matrix components from tissues. Our ...
ORGANISM(S): Rat 
GPM32310006954 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling of rats treated with chronic doses of anti-epilepsy drugs to identify genes involved in epileptogenesis
Epilepsy is a major neurological disorder that affects approximately 1% of the population. The processes that lead to the development of epilepsy (epileptogenesis) are largely unknown. Levetiracetam is a novel antiepileptic drug (AED) that in the kindling model inhibits epileptogenesis in addition t...
ORGANISM(S): Rattus norvegicus 
2007-08-01 | E-GEOD-2880 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood from patients with acute kidney injury following open-heart surgery with cardiopulmonary bypass
Acute kidney Injury (AKI) following open-heart surgery with cardiopulmonary bypass (CPB) is associated with an increased morbidity and mortality. The goal of this study is to explore patterns of gene expression in human AKI following CPB. This prospective observational study was approved by the Inst...
ORGANISM(S): Homo sapiens 
2009-12-12 | E-TABM-595 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertensive and normotensive rats treated with the AT1 receptor antagonist candesartan and vehicle
In hypertension, abnormal regulation of microcirculation and endothelial dysfunction enhances vulnerability to hypertensive brain damage. In addition to lowering blood pressure, blockade of Angiotensin II AT1 receptors protects against stroke and stress in different animal models and this treatment ...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2739 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of the response of Rattus norvegicus P15 and P30 hippocampus samples treated with kainate
This SuperSeries is composed of the following subset Series:; GSE1831: Temporal analysis of P15 hippocampus in kainate-induced seizures. Koh-2K08NS002068-04; GSE1834: Temporal analysis of hippocampus in kainate-induced seizures. Koh-7K08NS002068-05-3 Experiment Overall Design: Refer to individual ...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-4236 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rats subjected to hypoxic preconditioning or sham conditioning at several time points from 0 to 24 hrs after preconditioning
Hypoxic-ischemic (HI) injury in the developing brain is a common cause of disability in children, and there are no effective treatments at this time. Exposure to sublethal hypoxic conditions (hypoxic preconditioning) 24 hours prior to hypoxic-ischemic insult is protective in the developing rat mode...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-4753 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse P15 hippocampus in kainate-induced seizures
Early childhood convulsions have been correlated with hippocampal neuron loss in patients with intractable temporal lobe epilepsy. Using a "two-hit" rat seizure model, we have shown that animals subjected to kainate (KA)- or hypoxia-induced seizures during early postnatal period showed no cell deat...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1831 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat hippocampus response to ketone bodies
Diets characterized by increased blood levels of ketone bodies can protect the brain against a variety of acute and chronic neurological diseases. Moreover, ketone bodies are neuroprotective in many in vitro models of neurological injury. The underlying mechanisms remain unknown however. Recently, w...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7323 | biostudies-arrayexpress
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