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Bombesin receptor subtype-3 (BRS3) is an orphan G-protein coupled receptor (GPCR) that involved in a range of pathological and physiological processes, while its biological functions and underlying regulatory mechanisms remain largely unknown. Quantitative phosphoproteomics approach was employed in ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-12 | PXD035666 | Pride
Melanoma is a common type of cancer, and metastasis remains the leading cause for mortality in melanoma patients. In this study, we utilized an unbiased mass spectrometry-based quantitative proteomic method to assess, at the global proteome scale, differential protein expression in a matched pair of...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD014368 | Pride
Cashmere is regarded as a specialty and luxury fiber due to its scarcity and high economic value. For fiber quality assessment, it is technically very challenging to distinguish and quantify the cashmere fiber from yak or wool fibers because of their highly similar physical appearance and substantial...
ORGANISM(S): Bos mutus grunniens (Wild yak) (Bos grunniens) Ovis aries Capra hircus (Goat) 
2018-10-25 | PXD003107 | Pride
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
Proteomic profiling of the RAD52 interactome was performed by immunoprecipitation followed by mass spectrometry (IP-MS). RAD52-Flag was immunoprecipitated from HEK293T cells upon depletion of CPSF6 (with shCPSF6) or under control conditions (shNC). The co-precipitated proteins were then identified b...
ORGANISM(S): Homo sapiens (Human) 
2026-10-27 | PXD070757 | Pride
Fertilization triggers a dynamic symphony of molecular transformations induced by a rapid rise in intracellular calcium. Most prominent are surface alterations, metabolic activation, cytoskeletal reorganization, and cell cycle reentry. While the activation process appears to be broadly evolutionaril...
ORGANISM(S): Strongylocentrotus purpuratus (Purple sea urchin) 
2015-08-04 | PXD002239 | Pride
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