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ProteomicsGMPS promoting tumor immune evasion by regulating the glycosylation modification of PD-L1
Hepatocellular carcinoma (HCC) is a malignant tumor characterized by rapid progression, whose development is attributed to severe immune evasion. Here, we conducted proteomic and scRNA-Seq analysis on advanced HCC tissues and identified a significant molecule, Guanine monophosphate synthase (GMPS). ...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD045485 | Pride
Ptm Hcc Pd-l1 Immunotherapy 
UnknownFabrication of 3D Printed Polylactic Acid/Polycaprolactone Nanocomposites with Favorable Thermo-Responsive Cyclic Shape Memory Effects, and Crystallization and Mechanical Properties.
Not available
S-EPMC10053012 | biostudies-literature
UnknownTranscriptome Analysis Reveals Putative Induction of Floral Initiation by Old Leaves in Tea-Oil Tree (Camellia oleifera 'changlin53').
Not available
S-EPMC9655362 | biostudies-literature
UnknownRapid detection of goose astrovirus genotypes 2 using real-time reverse transcription recombinase polymerase amplification.
Not available
S-EPMC10629041 | biostudies-literature
ProteomicsMass spectrometry detected proteins interacting with DPP4 in C28/I2 cells
To understand the mechanisms responsible for DPP4 in osteoarthritis, we examined the proteins that interact with DPP4 using IP followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-07-30 | PXD054366 |
UnknownEfficacy and safety of LY01005 versus goserelin implant in Chinese patients with prostate cancer: A multicenter, randomized, open-label, phase III, non-inferiority trial.
Not available
S-EPMC10278759 | biostudies-literature
ProteomicsSilicon-rhodamine-enabled Identification (SeeID) for Near-Infrared Light Controlled Proximity Labeling In Vitro and In Vivo
Advancement in fluorescence imaging techniques enables the study of protein dynamics and localization with unprecedented spatiotemporal resolution. However, current imaging tools are unable to elucidate dynamic protein interactomes underlying imaging observations. In contrast, proteomics tools such ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-08-11 | PXD067243 |
ProteomicsLiquid chromatography-mass spectrometry based tissue metabolic profiling reveals major metabolic pathway alterations and potential biomarkers of lung cancer
MS spectrum of lung tissue metabolic analysis in 131 patients with lung cancer or benign lung tumor. These include lung cancer tissues/benign tumor tissues, adjacent normal tissues and distal normal tissues.
ORGANISM(S): Cancer 
2020-06-19 | PXD019969 |
ProteomicsThe sequence of Fully Synthetic peptides, Phosphorylated Tau181, Tau217, and Tau231 Calibrators, have been confirmed by MALDI-ISD analysis
We designed novel calibrators that include three phosphorylated Tau sites: Tau (1-22)-pT231, Tau (1-22)-pT217, and Tau (1-22)-pT181, respectively. Our synthesized peptides have various advantages compared with GSK3β-phosphorylated Tau-441. The novel fully synthesized calibrators not only improved th...
ORGANISM(S): Homo Sapiens 
2023-11-24 | PXD047248 |
ProteomicsPRMT3 reverses HIV-1 latency by increasing chromatin accessibility to form a TEAD4-P-TEFb-containing transcriptional hub
A major challenge to the current efforts to cure HIV-1 infection is the persistence of latent viruses. Addressing this challenge hinges on unraveling the intricate interplay between the host and viral factors that are key for HIV-1 latency. Current antiretroviral agents effectively prevent actively ...
ORGANISM(S): Homo Sapiens 
2025-03-25 | PXD062187 |
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