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ProteomicsSir4 H-BRCT domain interacts with multiple phospho-proteins to regulate heterochromatic repression
In Saccharomyces cerevisiae, the Silent Information Regulator (SIR) proteins Sir2/3/4 form a complex suppressing transcription of genes at subtelomeric regions and the homothallic mating type (HM) loci. Here we identify a non-canonical BRCA1 C-terminal domain (H-BRCT) in Sir4 which is responsible fo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-09-13 | PXD014119 | Pride
Tom1 Sir complex Heterochromatin Brct Dbf4 
UnknownStructure of Chimpanzee Gut Microbiomes across Tropical Africa.
Not available
S-EPMC8269259 | biostudies-literature
ProteomicsUtilization of alpha- and beta-mannan by marine Flavobacteriia
About one half of the global, biogenic carbon dioxide fixation into organic matter is driven by microscopic algae in the surface oceans. These microalgal activities generate, among other molecules, polysaccharides that are food for and recycled by bacteria with polysaccharide utilization loci (PULs)...
ORGANISM(S): Leeuwenhoekiella sp. MAR_2009_132 
2018-10-17 | PXD009066 | Pride
Leeuwenhoekiella Marine Mannan Polysaccharide 
ProteomicsUtilization of alpha- and beta-mannan by marine Flavobacteriia
About one half of the global, biogenic carbon dioxide fixation into organic matter is driven by microscopic algae in the surface oceans. These microalgal activities generate, among other molecules, polysaccharides that are food for and recycled by bacteria with polysaccharide utilization loci (PULs)...
ORGANISM(S): Salegentibacter sp. Hel_I_6 
2018-10-17 | PXD009080 | Pride
Leeuwenhoekiella Marine Proteomics Polysaccharide Degradation Salegentibacter 
UnknownCongenital secretory diarrhoea caused by activating germline mutations in GUCY2C.
Not available
S-EPMC4975829 | biostudies-literature
TranscriptomicsSystematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for microRNAs in Suppressing Basal Activation of the C. elegans Pathogen Response
Gene regulation by microRNAs (miRNAs) under specific physiological conditions often involves complex interactions between multiple miRNAs and a large number of their targets, as well as coordination with other regulatory mechanisms, limiting the effectiveness of classical genetic methods to identify...
ORGANISM(S): Caenorhabditis elegans 
2012-03-23 | E-GEOD-36419 | biostudies-arrayexpress
TranscriptomicsHiC-sequencing in human monocyte differentiation (3D-MO)
This dataset consists of in situ HiC-seq data from human monocytes, monocyte-derived dendritic cells as well as monocyte-derived cells that were subjected to siRNA treatment targeting CTCF or RAD21. In total, the data set includes 42 samples.
ORGANISM(S): Homo sapiens 
2022-06-24 | E-MTAB-10848 | biostudies-arrayexpress
UnknownClinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Not available
S-EPMC10981692 | biostudies-literature
GenomicsEGAS00000000092-ega-27092011 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000044 | EGA
GenomicsEGAS00000000092-ega-20110419 2 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000023 | EGA
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