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TranscriptomicsDepletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression
Inappropriate cross talk between mammals and their gut microbiota may trigger intestinal inflammation and drive extra-intestinal immune-mediated diseases. Studies with germ-free or gnotobiotic animals represent the gold standard for research on bacterial-host interaction but they are not readily acc...
ORGANISM(S): Mus musculus 
2011-08-14 | E-GEOD-22648 | biostudies-arrayexpress
Genomics16S sequencing of gut microbiota in healthy individuals from different regions
In this study we investigated whether gut microbiota profile of Italian healthy volunteers could differ based on their geaographical origin. To this purpose, fecal samples were collected from 31 healthy individuals living in 3 different italian regions (Lombardy, North; Lazio, Center; Apulia, South)...
ORGANISM(S): human gut metagenome 
2026-01-08 | E-MTAB-8136 | biostudies-arrayexpress
MetabolomicsA defined community of core gut microbiota members promotes cognitive performance in honey bees

Gut microbiota across animals have been shown to influence host cognition and behavior. However, it remains unclear whether these cognitive effects are driven by specific bacterial species or arise from community-level interactions. Here, we leveraged the honey bee (Apis mellifera) as a ...

2026-05-21 | MTBLS13943 | MetaboLights
MetabolomicsXuezhikang Ameliorating Non-Alcoholic Fatty Liver Disease via the Gut Microbiota-Metabolite-Ferroptosis Axis: A Multi-Omics Study
Objective: This study investigated the therapeutic mechanism by which Xuezhikang (XZK) alleviates non-alcoholic fatty liver disease (NAFLD) in mice, with a specific focus on the interplay between the gut microbiota, metabolic alterations, and hepatic ferroptosis. Methods: An NAFLD mouse model was in...
2026-06-16 | MTBLS14743 | MetaboLights
TranscriptomicsCharacterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Bacteroides thetaiotaomicron 
2010-05-22 | E-GEOD-14737 | biostudies-arrayexpress
MetabolomicsGut microbiota carcinogen metabolism causes distal tissue tumours

Exposure to environmental pollutants and human microbiome composition are important predisposition factors for tumour development. Similar to drug molecules, pollutants are typically metabolised in the body, which can change their carcinogenic potential and impact tissue distribution through alte...

2024-06-05 | MTBLS3581 | MetaboLights
MetabolomicsAlterations in gut microbiota and metabolomic profiles in acute stroke: insights into brain–gut axis dysregulation

Acute stroke (AS) is a major public health issue globally, exhibiting high morbidity, disability rate, and mortality. Emerging research has demonstrated the critical roles of gut microbiota and its metabolites in pathogenesis, recovery, and prognosis of AS. In this study, we investigated alterati...

2025-08-06 | MTBLS12822 | MetaboLights
ProteomicsMetaproteomics investigation on the gut microbiota of children affected by Autism Spectrum Disorder
Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives
ORGANISM(S): Bacteria (ncbitaxon:2) 
2020-04-06 | MSV000085232 | MassIVE
MetabolomicsHost-gut microbiota interactions shape parasite infections in farmed Atlantic salmon

Animals and their associated microbiota share long evolutionary histories. However, it is not always clear how host genotype and microbiota interact to affect phenotype. We applied a hologenomic approach to explore how host-microbiota interactions shape lifetime growth and parasite infection in f...

2024-01-24 | MTBLS8575 | MetaboLights
MetabolomicsGut microbiota-driven regulation of queen bee ovarian metabolism

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
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