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TranscriptomicsTranscription profiling by array of human T-cell differentiation
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T-cell developmental stages, including CD34+ lin- cord blood cells as a reference. The...
ORGANISM(S): Homo sapiens 
2005-07-01 | E-MEXP-337 | biostudies-arrayexpress
ProteomicsComparative cell surface proteomic analysis of the primary human T cell and monocyte responses to type I interferon
The cellular response to interferon (IFN) is essential for antiviral immunity, IFN-based therapy and IFN-related disease. The plasma membrane (PM) provides a critical interface between the cell and its environment, and is the initial portal of entry for viruses. Nonetheless, the effect of IFN on PM ...
ORGANISM(S): Homo sapiens (Human) 
2021-02-09 | PXD022834 | Pride
T cell Leukocytes Cell surface Antiviral restriction Monocyte Quantitative proteomics Interferon type i (ifn) Plasma membrane 
GenomicsA Distinct CAR-T Cell Phenotype Mediates Therapeutic Response at Limited Doses
A Distinct CAR-T Cell Phenotype Mediates Therapeutic Response at Limited Doses
PRJNA1391527 | ENA
TranscriptomicsGenome-wide RNA expression analysis of mouse spleens in parent-into-F1 lupus immune response
Analysis of whole spleen tissue expression signature in divergent responses from two parent-into-F1 lupus mouse model systems. The hypothesis is that strain differences of CD4 T cells exhibit difference lupus-inducing proclivity. Total RNA obtained from recipient mouse spleen at day 14 post-engraft...
ORGANISM(S): Mus musculus 
2015-09-02 | E-GEOD-71611 | biostudies-arrayexpress
ProteomicsPhosphoproteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Targetable Kinases and Combination Treatments
Protein kinase inhibitors are amongst the most successful cancer treatments, but targetable kinases activated by gene fusions are rare in T-ALL (e.g., NUP214-ABL1). Nevertheless, leukemic blasts rely on enhanced kinase signaling to sustain dysregulated proliferation. Protein kinases can be hyper-act...
ORGANISM(S): Homo sapiens (Human) 
2022-02-21 | PXD024807 | Pride
Human Single-shot T-all Ptyr Label-free Phosphoproteomics T-cell acute lymphoblastic leukemia 
TranscriptomicsArabidopsis thaliana ecotype Col-0 versus T-DNA mutant sir1-1
Arabidopsis thaliana Col-0 plants were compared to sir1-1 T-DNA insertion mutants to investigate transcript levels of sulfur metabolism related genes under standard conditions. For wildtype Col-0 and sir1-1, leaf tissue was harvested from 3 independent plants that were 7 weeks old; total RNA was ext...
ORGANISM(S): Arabidopsis thaliana 
2010-05-05 | E-GEOD-20670 | biostudies-arrayexpress
UnknownImmunometabolic Adaptation of CD19-Targeted CAR T Cells in the Central Nervous System Microenvironment of Patients Promotes Memory Development.
Not available
S-EPMC10984768 | biostudies-literature
UnknownQuantum Hall effect at 0.002 T in graphene.
Not available
S-EPMC12936209 | biostudies-literature
UnknownEmergent Thermal Strain-Induced Pseudomagnetic Fields and Shubnikov-de Haas Beating Patterns in Encapsulated Graphene in Extraordinary Magnetoresistance Geometry.
Not available
S-EPMC12368988 | biostudies-literature
UnknownShubnikov-de Haas oscillations, weak antilocalization effect and large linear magnetoresistance in the putative topological superconductor LuPdBi.
Not available
S-EPMC4361847 | biostudies-literature
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