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MetabolomicsProfiling aromatic amino acid metabolome in the human gut microbiota reveals Clostridioides difficile specific N-acyl amino acids

Owing to its compositional and chemical complexity, much of the gut microbiota metabolome remains poorly characterized. Aromatic amino acids (AAAs) have a history of being privileged substrates for the biosynthesis of diverse bioactive metabolites and thus represent a potentially rich source of b...

2026-07-23 | MTBLS13404 | MetaboLights
ProteomicsCavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
Caveolae-associated protein 3 (cavin3), a putative tumor suppressor protein, is inactivated in most cancers. The molecular basis for its actions remains poorly understood. We characterized the effects on the proteome of cavin3 loss by utilizing genome-edited cells together with label-free quantitati...
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD026724 | Pride
Breast cancer Caveolae Cavin proteins Brca1 
ModelsGould2013 - Temperature Sensitive Circadian Clock
Gould2011 - Temperature Sensitive Circadian Clock This model is a temperature sensitive version of Pokhilko et al.  2010 (PMID: 20865009), which is BIOMD0000000273 in BioModels. This model is described in the article: Network balance via CRY signalling controls the Arabidopsis circa...
2024-09-02 | BIOMD0000000564 | BioModels
ProteomicsProteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander trafficking complex, which depends on the C-terminus of...
ORGANISM(S): Homo sapiens (Human) 
2022-11-07 | PXD036424 | Pride
Endosome Pdz domain Snx17 Commander Retriever Pdlim 
TranscriptomicsInhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities, but not Inflammation and Injury in Mice
Abnormalities in hepatic lipid metabolism are believed to play a critical role in the etiology of nonalcoholic steatohepatitis (NASH). Monoacylglycerol acyltransferase (MGAT) enzymes convert monoacylglycerol to diacylglycerol, which is the penultimate step in one pathway for triacylglycerol (TAG) sy...
ORGANISM(S): Mus musculus 
2014-11-05 | E-GEOD-60349 | biostudies-arrayexpress
MetabolomicsResolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling
Corals continuously adjust to short term variation in light availability on shallow reefs. Long-term light alterations can also occur due to natural and anthropogenic stressors, as well as management interventions such as coral transplantation. Although short term photophysiological responses are re...
2019-04-11 | MTBLS768 | MetaboLights
UnknownGenetic structuring and fixed polymorphisms in the gene period among natural populations of Lutzomyia longipalpis in Brazil.
Not available
S-EPMC4409732 | biostudies-literature
UnknownDeltamethrin and transfluthrin select for distinct transcriptomic responses in the malaria vector Anopheles gambiae.
Not available
S-EPMC10476409 | biostudies-literature
UnknownPrecursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family.
Not available
S-EPMC7268733 | biostudies-literature
MetabolomicsCascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
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