Sort   by:  
 Page size 
ProteomicsProteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander trafficking complex, which depends on the C-terminus of...
ORGANISM(S): Homo sapiens (Human) 
2022-11-07 | PXD036424 | Pride
Endosome Pdz domain Snx17 Commander Retriever Pdlim 
ProteomicsPhosphorylation of SNX17 impedes activation of Retriever-mediated sorting
Sorting nexin 17 (SNX17) functions as cargo receptor on endosomal membranes that enables the recycling of numerous membrane cargo proteins by binding to the Retriever complex. Yet, little is known how SNX17 activity or its membrane recruitment is regulated. Here, we report that phosphorylation of SN...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-06-30 | PXD061808 | Pride
Endosome Intracellular trafficking Sorting nexin Retriever Phosphorylation Integrin Phox domain 
ProteomicsRetriever is a multiprotein complex for retromer-independent endosomal cargo recycling
Following endocytosis into the endosomal network, integral membrane proteins undergo sorting for lysosomal degradation or are retrieved and recycled back to the cell surface. Here we describe the discovery of an ancient and conserved multiprotein complex which orchestrates cargo retrieval and recycl...
ORGANISM(S): Homo sapiens (Human) 
2018-01-15 | PXD007230 | Pride
Snx17 Retriever Retromer 
UnknownPhosphorylation of SNX17 impedes activation of Retriever-mediated sorting.
Not available
S-EPMC12182294 | biostudies-literature
UnknownStructural basis for Retriever-SNX17 assembly and endosomal sorting.
Not available
S-EPMC10980035 | biostudies-literature
UnknownStructural basis for Retriever-SNX17 assembly and endosomal sorting.
Not available
S-EPMC11589680 | biostudies-literature
UnknownSNX17 affects T cell activation by regulating TCR and integrin recycling.
Not available
S-EPMC4402276 | biostudies-literature
UnknownSelective cargo and membrane recognition by SNX17 regulates its interaction with Retriever.
Not available
S-EPMC11772769 | biostudies-literature
UnknownRecruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity.
Not available
S-EPMC10165670 | biostudies-literature
UnknownSNX17 mediates STAT3 activation to promote hepatocellular carcinoma progression via a retromer dependent mechanism.
Not available
S-EPMC12035908 | biostudies-literature
Sort   by:  
 Page size