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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
ProteomicsIn depth proteome analyais of primary human nasal epithelium induced by diesel exhaust particles
Diesel exhaust particles (DEPs), a major component of airborne particulate matter (PM), are strongly associated with the development of both acute and chronic upper airway inflammatory diseases. In this study, we investigated the effects of prolonged daily exposure to low-dose DEPs on the maturation...
ORGANISM(S): Homo sapiens (Human) 
2026-05-23 | PXD065940 | Pride
Diesel exhaust particles Human nasal epithelium Tmt 
MetabolomicsA Multi-Omics Analysis of Glycine max Leaves Reveals Alteration in Flavonoid and Isoflavonoid Metabolism Upon Ethylene and Abscisic Acid Treatment
Phytohormones are central to plant growth and development. Despite the advancement in our knowledge of hormone signaling, downstream targets, and their interactions upon hormones action remain largely fragmented, especially at the protein and metabolite levels. With an aim to get new insight into th...
2018-09-20 | MTBLS531 | MetaboLights
UnknownSuperior protective effects of PGE2 priming mesenchymal stem cells against LPS-induced acute lung injury (ALI) through macrophage immunomodulation.
Not available
S-EPMC10032272 | biostudies-literature
UnknownComparative analysis of oral saliva microbiomes and metabolites in Han population at different altitudes.
Not available
S-EPMC11610449 | biostudies-literature
GenomicsIgA Nephropathy GWAS (IGANGWAS)

We report a genome-wide association study of IgA nephropathy, a main cause of kidney failure. All subjects were of Chinese Han ancestry, of which 1,194 were cases and 902 controls. Genomic DNA samples extracted from whole blood were genotyped on the Illumina 610 Quad platform.

phs000431.v1.p1 | EGA
TranscriptomicsExpression levels in strained vs. non-strained Calu-3 lung epithelial cells
Ventilator induced lung injury can lead to serious conditions like ARDS which are associated with a high mortality (around 30%, Stapleton et al., Chest, 2005). We hypothesized that changes of expression levels of different genes would lead us to the identification of critical target genes, which mig...
ORGANISM(S): Homo sapiens 
2011-02-12 | E-GEOD-27128 | biostudies-arrayexpress
GenomicIgA Nephropathy GWAS (IGANGWAS)

In this second study version, we report a genome-wide association study of IgA nephropathy performed in individuals of European ancestry (US and Italian cohorts), followed by a meta-analysis with the existing GWAS cohorts (Han Chinese [study version 1] and French cohorts). Genomic DNA was extrac...

phs000431 | dbGaP
ProteomicsDefining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus
Enteric bacterial pathogens pose significant threats to human health; however, the mechanisms by which they infect the mammalian gut in the face of daunting host defenses remain to be fully defined. For the attaching and effacing (A/E) bacterial family member and murine pathogen Citrobacter rodentiu...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-17 | PXD061145 | Pride
Espc Mucus Air-liquid interface Colonoids Enteric pathogens 
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