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Intraductal papillary mucinous neoplasm (IPMN) is a duct-dilating precancerous lesion that grows in pancreatic ducts and is accompanied by the production of mucinous fluid. In recent years, its cystic fluid has been used molecularly for the differential diagnosis of other cystic tumors and malignanc...
ORGANISM(S): Homo sapiens (Human) 
2017-08-22 | PXD005671 | Pride
Among multiple interconnected pathways for L-Lysine (L-Lys) catabolism in pseudomonads, Pseudomonas aeruginosa PAO1 employed the decarboxylase and the transaminase pathways. However, up till now several genes involved in the operation and regulation of these pathways were still missing. Transcriptom...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
Triple negative breast cancer (TNBC) is characterized by an aggressive biologic behavior without specific targeted agent. Nicotinamide has recently been proven as a novel therapeutic agent for skin tumors in ONTRAC trial. Here we performed in-depth proteomes to characterize network of molecular inte...
ORGANISM(S): Homo sapiens (Human) 
2017-06-20 | PXD005304 | Pride
Urine cytologic examination is a widely used primary pathologic screening test in the diagnosis of bladder urothelial carcinoma (BLCA), however the low diagnostic accuracy remains challenging. We conducted high-throughput proteome on ten pairs of BLCA and benign urothelial lesion (BUL) to identify a...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD006805 | Pride
Metabolic dysregulation of neurons is associated with diverse human brain disorders. Metabolic reprogramming occurs during neuronal differentiation, but it is not fully understood which molecules regulate metabolic changes at the early stages of neurogenesis. In this study, we report that miR-124 is...
ORGANISM(S): Homo sapiens (Human) 
2024-10-13 | PXD042371 | Pride
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