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ProteomicsIn-depth protein profiling of cytology samples in urothelial carcinoma
Urine cytologic examination is a widely used primary pathologic screening test in the diagnosis of bladder urothelial carcinoma (BLCA), however the low diagnostic accuracy remains challenging. We conducted high-throughput proteome on ten pairs of BLCA and benign urothelial lesion (BUL) to identify a...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD006805 | Pride
Human Liquid biopsy Label free quantification Cytology Quantitative proteomics 
MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
ProteomicsQuantitative proteomic analysis of urine liquid biopsy samples in muscle invasive bladder urothelial carcinoma
We performed mass spectrometry-based proteomic analysis of urine samples of patients with BLCA with stroma invasion or muscle invasion to identify prognosis markers for use in liquid-based cytology (LBC).
ORGANISM(S): Homo sapiens (Human) 
2020-04-29 | PXD016437 | Pride
Human Lable free quantification Cytology Urothelial carcinoma Urine 
TranscriptomicsPreoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
BACKGROUND: Following fine needle aspiration, 15-30% of thyroid nodules are not clearly benign or malignant. These cytologically indeterminate nodules are often referred for diagnostic surgery, though most prove benign. A novel diagnostic test measuring the expression of 167 genes has shown promise ...
ORGANISM(S): Homo sapiens 
2012-06-24 | E-GEOD-34289 | biostudies-arrayexpress
UnknownEvaluating cytology for the detection of invasive cervical cancer.
Not available
S-EPMC4913744 | biostudies-literature
UnknownProtocol for Compass: a randomised controlled trial of primary HPV testing versus cytology screening for cervical cancer in HPV-unvaccinated and vaccinated women aged 25-69 years living in Australia.
Not available
S-EPMC5829592 | biostudies-literature
TranscriptomicsGene-expression profiles of ascites-cytology-positive ovarian cancer
Ovarian cancer often progresses by disseminating to the peritoneal cavity, but how the tumor cells evade host immunity during this process is poorly understood. Programmed cell death 1 ligand 1 (PD-L1) is known to suppress immune system and to be an unfavorable prognostic factor in ovarian cancer. T...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-39204 | biostudies-arrayexpress
TranscriptomicsGene-expression profiles of ascites-cytology-positive ovarian cancer
Ovarian cancer often progresses by disseminating to the peritoneal cavity, but how the tumor cells evade host immunity during this process is poorly understood. Programmed cell death 1 ligand 1 (PD-L1) is known to suppress immune system and to be an unfavorable prognostic factor in ovarian cancer. T...
ORGANISM(S): Homo sapiens 
2012-07-10 | GSE39204 | GEO
TranscriptomicsBIGenomics_hpv_Agilent
Human papillomavirus infection is the cause of essentially all cases of cervical premalignant lesions and cervical cancer. Primary screening using HPV DNA testing with cytology triage has been shown to be more sensitive and, importantly, more specific than conventional testing based on cytology amon...
ORGANISM(S): Human papillomavirus 
2011-12-10 | E-MEXP-3466 | biostudies-arrayexpress
UnknownSensitivity of cytology in liver tumor biopsy and its significance in the prompt clinical diagnosis of non-hepatocellular carcinoma.
Not available
S-EPMC10278471 | biostudies-literature
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