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TranscriptomicsGenome-wide screening of mRNA expression in leprosy patients
In this study, a comprehensive assessment of human mRNA was performed on leprosy skin lesions using DNA chip microarrays, which included the entire spectrum of the disease along with its reactional states. Sixty-six samples from leprotic lesions (10TT, 10BT, 10BB, 10BL, 4LL, 14R1, and 10R2) and nine...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-74481 | biostudies-arrayexpress
ProteomicsDDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II
Transcription-blocking DNA lesions are specifically targeted by transcription-coupled nucleotide excision repair (TC-NER), which removes a broad spectrum of DNA lesions to preserve transcriptional output and thereby cellular homeostasis to counteract aging. TC-NER is initiated by the stalling of RNA...
ORGANISM(S): Homo sapiens (Human) 
2024-05-02 | PXD051638 | Pride
Crl4csa Rna polymerase ii Dna damage Dda1 Transcription-coupled repair 
UnknownApplication of an obstetric comorbidity index to predict childhood cancer risk: a population based case-control study in Denmark.
Not available
S-EPMC12449446 | biostudies-literature
ProteomicsTranslational activity of the splicing factor SRSF1 is required for development and cilia function
The SR protein family of splicing factors regulate constitutive and alternative pre-mRNA splicing. A subset of them, including SRSF1, shuttles continuously between the nucleus and cytoplasm affecting post-splicing processes. We have previously identified a role for SRSF1 in promoting the translation...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-06 | PXD019859 | Pride
Sr proteins/ srsf1/ mrna translation/ alternative splicing/ cilia 
TranscriptomicsImplications of high level pseudogene transcription in Mycobacterium leprae
Approximately half of M. lepraeâ??s transcriptome consists of inactive gene products. This has an impact on overall energy and resource consumption without potential benefit to this organism. However, multiple translational â??silencingâ?? mechanisms are present, reducing additional energy and resou...
ORGANISM(S): Mycobacterium leprae 
2010-06-24 | E-GEOD-17191 | biostudies-arrayexpress
UnknownMaternal diabetes and childhood cancer risks in offspring: two population-based studies.
Not available
S-EPMC9643384 | biostudies-literature
UnknownParental occupation and childhood germ cell tumors: a case-control study in Denmark, 1968-2016.
Not available
S-EPMC8236473 | biostudies-literature
UnknownFetal programming and Wilms tumor.
Not available
S-EPMC6530460 | biostudies-literature
UnknownDrugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Not available
S-EPMC8392692 | biostudies-literature
UnknownOccupational livestock or animal dust exposure and offspring cancer risk in Denmark, 1968-2016.
Not available
S-EPMC7261625 | biostudies-literature
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