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UnknownMetabolic-driven analytics of traumatic brain injury and neuroprotection by ethyl pyruvate.
Not available
S-EPMC11562096 | biostudies-literature
TranscriptomicsFunctional Genomics Analysis of the Yeast Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions
The Saccharomyces cerevisiae transcription factor Aft1 is activated in iron-deficient cells to induce the expression of iron regulon genes, which coordinate the increase of iron uptake and remodel cellular metabolism to survive low iron conditions. In addition, Aft1 has been implicated in numerou...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-01 | E-GEOD-20531 | biostudies-arrayexpress
UnknownGene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.
Not available
S-EPMC9256753 | biostudies-literature
TranscriptomicsEffect of salicylic acid on Fusarium graminearum, the major causal agent of fusarium head blight in wheat
Salicylic acid (SA) is one of the key signal molecules in regulating plant resistance to diverse pathogens. It is predominantly associated with resistance against biotrophic and hemibiotrophic pathogens, and triggering systemic acquired resistance (SAR) in Arabidopsis. However, whether and how SA di...
ORGANISM(S): Gibberella zeae 
2011-12-15 | E-GEOD-24636 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse ears exposed to sulfur mustard alone, sulfur mustard preceded by drug treatment, or vehicle compounds to identify gene expression changes that correlate with compound efficacy
Sulfur mustard (SM) is a potent alkylating agent. We are developing medical countermeasures to reduce the injury caused by SM exposure. Screening in the mouse ear vesicant model has identified three effective compounds: dimercaprol (British anti-lewisite), indomethacin, and octyl homovanillamide (OH...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-2950 | biostudies-arrayexpress
GenomicsThe genomic complexity of early T-cell progenitor acute lymphoblastic leukemia

CREST

The accurate identification of structural variations using whole-genome DNA sequencing data generated by next-generation sequencing technology is extremely difficult. To address this challenge, we have developed CREST, an algorithm that uses sequencing reads with partial align...

phs000340.v2.p1 | EGA
UnknownHeterogeneity in association of remote herpesvirus infections and pediatric MS.
Not available
S-EPMC6186938 | biostudies-literature
TranscriptomicsA Signaling Lipid Associated with Alzheimer’s Disease Promotes Mitochondrial Dysfunction
Fundamental changes in the composition and distribution of lipids within the brain are believed to contribute to the cognitive decline associated with Alzheimer’s disease (AD). The mechanisms by which these changes in lipid composition affect cellular function and ultimately cognition are not well...
ORGANISM(S): Saccharomyces cerevisiae 
2016-01-21 | E-GEOD-40814 | biostudies-arrayexpress
UnknownMultiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Not available
S-EPMC3371395 | biostudies-literature
TranscriptomicsMerging candidate gene approach with high throughput systems biology technology for the development of xylose utilising S. cerevisiae strains
Though highly efficient at fermenting hexose sugars, the ethanologenic yeast Saccharomyces cerevisiae has limited ability to ferment five-carbon sugars. As a significant portion of sugars found in cellulosic biomasses is the five carbon sugar xylose, S. cerevisiae must be engineered to metabolize pe...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-14 | E-GEOD-27325 | biostudies-arrayexpress
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