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ProteomicsHuman OTX2 TurboID Analysis in Transfected HDMB03 Cells
HDMB03 cells were transiently transfected with plasmids expressing NLS-TurboID or 3xHA-TurboID-OTX2 under the control of a strong CAG promoter. After a 15-minute pulse with 500 µM exogenous biotin, RIPA lysates were prepared and processed with streptavin-sepharose to capture biotinylated proteins th...
ORGANISM(S): Homo sapiens (Human) 
2024-05-31 | PXD052687 | Pride
Human Medulloblastoma Turboid Hdmb03 cells Otx2 Proximity labeling 
GenomicsEffect of CALCOCO2 depletion in HDMB03 Group 3 medulloblastoma cells
Effect of CALCOCO2 depletion in HDMB03 Group 3 medulloblastoma cells
PRJNA1436480 | ENA
ProteomicsProteomic profiling of nuclear fractions of SMARCA4 knockdown samples in HDMB03
SMARCA4 mutations are common in Medulloblastoma but not much is understood about its pathobiology. In this study we prepared SMARCA4 knockdown models using a Group 3 medulloblastoma cell line called HDMB03 and investigated the proteomic changes. Nuclear enrichment was performed using hypertonic and ...
ORGANISM(S): Homo Sapiens (human) 
2026-03-25 | PXD070641 | JPOST Repository
TranscriptomicsEffect of CALCOCO2 depletion in HDMB03 Group 3 medulloblastoma cells
Medulloblastoma (MB) is the most common malignant paediatric brain tumour, with Group 3 disease representing the most aggressive and therapy-refractory subtype. Despite intensive craniospinal radiotherapy, outcomes remain poor and the molecular basis of radioresistance is unclear. Here we identify C...
ORGANISM(S): Homo sapiens 
2026-09-01 | GSE324649 | GEO
UnknownImpact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis.
Not available
S-EPMC6070673 | biostudies-literature
GenomicsFailure of human rhombic lip differentiation constitutes medulloblastoma
Failure of human rhombic lip differentiation constitutes medulloblastoma
PRJNA826820 | ENA
GenomicsMedulloblastoma is a differentiation disorder of the human rhombic lip
Medulloblastoma is a differentiation disorder of the human rhombic lip
PRJNA782182 | ENA
ProteomicsProteomic profiling of in vitro knockdown of SMARCA4 in Medulloblastoma
SMARCA4 mutations are common in Medulloblastoma but not much is understood about its pathobiology. In this study we prepared SMARCA4 knockdown models using a Group 3 medulloblastoma cell line called HDMB03 and investigated the proteomic changes. We performed both DDA and DIA analyses and found that ...
ORGANISM(S): Homo Sapiens (human) 
2026-03-25 | PXD070640 | JPOST Repository
GenomicsReduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified meduloblastoma [expression]
Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified meduloblastoma [expression]
PRJNA600257 | ENA
GenomicsReduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified meduloblastoma [ChIP-seq]
Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified meduloblastoma [ChIP-seq]
PRJNA600250 | ENA
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