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ProteomicsProteomic analysis of the aggregated proteins in cerebral vessles from MYPT1SMKO mice
To comprehensively understand the mechanism by which MYPT1 modulates the phenotypic switching of VSMCs after ischemic stroke, the proteins of cortical small vessel from MYPT1SMKO and WT mice subjected to MCAO or sham group were collected for proteomic screening.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-21 | PXD027869 | Pride
Mypt1 Ischemmic stroke Vsmc Bbb 
UnknownMelatonin mitigates ovarian aging through regulation of the YTHDF2/m <sup>6</sup>A/UBE3C axis.
Not available
S-EPMC12536360 | biostudies-literature
UnknownA hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function.
Not available
S-EPMC5787817 | biostudies-literature
TranscriptomicsEffect of probiotic Lactobacillus casei Zhang on liver gene expression of hypercholesterolemic rats
The hypocholesterolemic effect of probiotics has been observed, but the molecular mechanism of probiotic-host interaction is still obscure. In this study, DNA microarray technology was used to explore the gene expression profile of liver of hypercholesterolemic rats caused by administration of probi...
ORGANISM(S): Rattus norvegicus 
2011-12-31 | E-GEOD-23740 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls
Skin fibroblasts from individuals with PBD-ZSD, a rare autosomal recessive disorder caused by peroxisome assembly defects, show defects in lipid metabolism that provide the basis for clinical diagnostic tests, but are not among the cell types most affected by disease. To explore phenotypes of more c...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-69066 | biostudies-arrayexpress
UnknownSustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins.
Not available
S-EPMC3940538 | biostudies-literature
UnknownDetection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing.
Not available
S-EPMC9485529 | biostudies-literature
UnknownImmunoglobulin M response in largemouth bass (<i>Micropterus salmoides</i>) following ranavirus infection.
Not available
S-EPMC11814181 | biostudies-literature
TranscriptomicsIdentification of miRNAs and their target genes in developing maize ears by deep sequencing
In plants, MicroRNAs (miRNAs) are a new class of endogenous small RNAs that play essential regulatory roles in plant growth, development and stress response. Extensive studies of miRNAs have been performed in model plants such as rice, Arabidopsis thaliana and other plants. However, the number of mi...
ORGANISM(S): Zea mays 
2014-10-22 | E-GEOD-47837 | biostudies-arrayexpress
UnknownAn oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis.
Not available
S-EPMC7125119 | biostudies-literature
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