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ProteomicsIdentification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7
Commander is an endosome associated sixteen protein assembly that associates with the sorting nexin 17 (SNX17) cargo adaptor to regulate cell surface recycling of internalised integral membrane proteins including integrins and lipoprotein receptors. Mutations in Commander are causative for Ritscher-...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD067193 | Pride
Human Lrmda Retriever Tmt label Melanocyte Rab32 Lc-ms/ms 
ProteomicsIdentification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition
The endosomal-lysosomal network is a hub of organelles that orchestrate the dynamic sorting of hundreds of integral membrane proteins to maintain cellular homeostasis. VPS29 is a central conductor of this network through its assembly into Retromer, Retriever and Commander endosomal sorting complexes...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD064959 | Pride
Commander Retriever Endosomes Lysosomes Retromer 
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S-EPMC10130092 | biostudies-literature
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S-EPMC3709460 | biostudies-literature
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S-EPMC8084355 | biostudies-literature
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S-EPMC8830904 | biostudies-literature
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S-EPMC8121538 | biostudies-literature
UnknownAspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
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S-EPMC8598213 | biostudies-literature
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