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ProteomicsLL10000 hybridization
The screening of a previously reported fluorescein labelled 10,000 member PNA encoded peptide library allowed information on the interaction between the peptide-ligands and the cell surface receptors to be extracted, identified new peptide ligands for cell surface receptors, and gave crucial informa...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-MEXP-3104 | biostudies-arrayexpress
TranscriptomicsThe deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways [HEK293T]
The function of DFNA5 remained unknown for a long time, but previous functional studies by Op de Beeck et al. (2011) revealed that DFNA5 induces a growth defect in mutDFNA5- transfected HEK293T cells, as well as other cells, leading to PCD (Op de Beeck et al., 2011). The cell death-inducing capacity...
ORGANISM(S): Homo sapiens 
2015-06-24 | E-GEOD-70167 | biostudies-arrayexpress
TranscriptomicsIntracellular and extracellular microRNAs expressed by HEK293T cells
MicroRNAs (miRNAs) are a class of small RNA molecules that regulate expression of specific mRNA targets. They can be released from cells, often encapsulated within extracellular vesicles (EVs), and therefore have the potential to mediate intercellular communication. It has been suggested that certai...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-GEOD-38916 | biostudies-arrayexpress
TranscriptomicsmRNA abundance in HEK293T cells mock or miR-124 transfected
HEK293T cells were either mock or miR-124 transfected. Cells were lysed 12 hours after transfection with Trizol reagent. RNA was isolated, amplified, labeled (cy5), and comparatively hybridized with a universal reference (cy3) on HEEBO arrays in biological triplicate. In addition, each biological re...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-18835 | biostudies-arrayexpress
ProteomicsTemporal Insights into Molecular and cellular responses during rAAV production in HEK293T cells
To understand the dynamic role of HEK293T cells at different cellular states post-transfection we have performed a comprehensive comparative proteome profiling of the host cell system post-transfection at 24, 48, and 72 hpt. For this study, we developed an in-house label-free HEK293T-AAV spectral li...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD046574 | Pride
Hek293t Spectral library Swath-ms 
ProteomicsProteome of Mpox virus A5L-expressing HEK293T cells
In this research, to discover the interactions of mpox-A5 with host proteins, HEK293T cells were utilized and transfected with pCAGGS-HA-A5L plasmid (or pCAGGS-HA plasmid), harvested at 24h, Heterologous expression of MPXV A5L in HEK293T cells was performed for Co-IP with anti-HA beads, and Immunobl...
ORGANISM(S): Homo Sapiens 
2024-11-13 | PXD057872 |
TranscriptomicsCUT&RUN experiment at four time points in HEK293T and hESC cells, assessing the time-resolved response of β-catenin genomic occupancy upon Wnt signaling activation
Wnt/β-catenin signaling is a highly organized biochemical cascade that triggers a gene expression program in the signal-receiving cell. The Wnt/β-catenin-driven transcriptional response is involved in virtually all cellular processes during development, homeostasis, and its deregulation causes human...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12077 | biostudies-arrayexpress
ProteomicsLILRA3-GFP and GFP only Transfected HEK293T cells LC-MSMS
The leukocyte immunoglobulin-like receptor A3 (LILRA3) is a soluble protein primarily expressed by peripheral blood monocytes and is abundant in sera of healthy donors. Extracellular LILRA3 is anti-inflammatory and displays neuro-regenerative functions in vitro. However, its intracellular expression...
ORGANISM(S): Homo sapiens (Human) 
2021-04-08 | PXD024602 | Pride
Lc-msms Immunoprecipitation Hek293t cells Lilra3 
ProteomicscircRIG-I associated proteins in HEK293T
We use Proximity biotinylation to find circRIG-I associated proteins in HEK293T.
ORGANISM(S): Homo sapiens (Human) 
2022-11-16 | PXD037928 | Pride
Circrig-i Hek293t 
ProteomicsIdentification of p62-interacting proteins by mass spectrometry analysis in HEK293T cells
HEK293T cells were ectopically expressing Flag tagged p62 (p62 group) or empty vectors (Control group) for 48h, cell lysates were incubated with anti-Flag affinity gels, and co-immunoprecipitates were subjected to trypsin digestion followed by mass spectrometry analysis. Peptides were separated by t...
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062511 | Pride
Hek293t cells P62 Mass spectrometry analysis 
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