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ProteomicsProteomic analysis of antigen-capturing nanoparticles
Immunotherapy holds tremendous promise for improving cancer treatment. Administering radiotherapy with immunotherapy has been shown to improve immune responses and can elicit an “abscopal effect”. Unfortunately, response rates for this strategy remain low. Herein, we report an improved cancer immuno...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-26 | PXD006049 | Pride
Nanoparticles Cancer immunotherapy 
TranscriptomicsSinus Microbiome Plays a Primary Role in Rhinosinusitis
Persistent mucosal inflammation and microbial infection are characteristic of Chronic Rhinosinusitis (CRS). Though mucosal microbiota dysbiosis is a characteristic feature of other chronic inflammatory diseases, the relationship between sinus microbiota composition and CRS is unknown. Here we demons...
ORGANISM(S): human nasopharyngeal metagenome 
2012-07-31 | E-GEOD-37850 | biostudies-arrayexpress
TranscriptomicsTrancription profiling of the hepatoma cell line Huh7 infected with the Hepatitis C Virus
Hepatitis C Virus is a leading cause of chronic liver disease. The identification and characterisation of key host cellular factors that play a role in the HCV replication cycle is important for the understanding of disease pathogenesis and the identification of novel anti-viral therapeutic targets....
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20948 | biostudies-arrayexpress
TranscriptomicsGenomeTiling
Samples were purchased from Clontech as mRNA. Hybridization material was generated through a random-priming amplification procedure (RP-AMP) using primers with a random sequence at the 3' end and a fixed motif at the 5' end. shDNP256 (first strand synthesis): 5'- TAG ATG CTG TTG NNN NNN NNN -3' sh...
ORGANISM(S): Homo sapiens 
2004-03-03 | E-GEOD-1097 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of cyanobacteria Prochlorococcus marinus subsp. pastoris str. CCMP1986 (MED4) and str. MIT 9313 grown in media with different levels and sources of nitrogen
Cyanobacteria Prochlorococcus marinus subsp. pastoris str. CCMP1986 (MED4) and Prochlorococcus marinus str. MIT 9313 (MIT9313) are oceanic oxygenic phototrophs, where MED4 is abundant in surface waters (~0-50 meters) and MIT9313 is abundant at depths of ~100 meters. To explore nitrogen-regulated cha...
ORGANISM(S): Prochlorococcus marinus 
2007-10-11 | E-TABM-91 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic kidney cells expressing apoptosis inducing proteins, time series
Three apoptosis inducing proteins, ACO1, STK3 and XBP1 were discovered in a previous reverse transfection screen. HEK293T cells were harvested and RNA extracted from the cells after over-expression of these 3 proteins at 12, 24 and 48 hours. A positive apoptosis inducer staurosporine and a negative ...
ORGANISM(S): Homo sapiens 
2005-09-05 | E-MEXP-421 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of alternative splicing in Caenorhabditis elegans
Alternative splicing (AS) plays a crucial role in the diversification of gene function and regulation. Consequently, the systematic identification and characterization of temporally regulated splice variants is of critical importance to understanding animal development. We have used high-throughput ...
ORGANISM(S): Caenorhabditis elegans 
2010-12-14 | E-GEOD-25927 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell lines and tissues (Novartis/GNF)
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-03-19 | E-MEXP-18 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 269 individuals from three geographically distinct human populations to investigate copy number variation
We conducted comparative genome hybridization experiments to catalogue the common copy number variation evident between 269 individuals from three geographically distinct human populations (Yoruban, Chinese/Japanese, European) against a single reference individual.
ORGANISM(S): Homo sapiens 
2006-07-31 | E-TABM-107 | biostudies-arrayexpress
UnknownIdentification of common variants associated with human hippocampal and intracranial volumes.
Not available
S-EPMC3635491 | biostudies-literature
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