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ProteomicsMulti-level microbial fingerprinting in anaerobic digestion reveals consistent fingerprinting profiles
The anaerobic digestion microbiomes has been puzzling us since the dawn of molecular methods for mixed microbial community analysis. Monitoring of the anaerobic digestion microbiome can either take place via a holistic evaluation of the microbial community through fingerprinting or by targeted monit...
ORGANISM(S): human gut metagenome anaerobic digester metagenome 
2021-05-26 | PXD024788 | Pride
16s rrna gene amplicon sequencing Anaerobic digestion Metabolomics Flow cytometry Microbial fingerprinting Metaproteomics 
ProteomicsNo evidence for major spacial differences within the microbial communities in anaerobic digestion plants under different feeding and stirring regimes
In anaerobic digestion plants (ADP) homogenization of the feed, the fermenter content and the microbial communities represents a precondition for effective and robust biogas production,but also a major energy consumer. For a 850 m3 agricultural AD-P equipped with eight sampling ports we investigated...
ORGANISM(S): Escherichia coli 
2021-04-27 | PXD016213 | Pride
Microbial communities Stirring Trflp Anaerobic digestion  biogas Metaproteomics 
ProteomicsAdaptation of a microbial community to demand-oriented biological methanation
Background: Biological conversion of the surplus of renewable electricity to CH4 could support energy storage and strengthen the power grid. Biological methanation (BM) is closely linked to the activity of biogas-producing bacterial community and methanogenic Archaea in particular. During reactor o...
ORGANISM(S): Escherichia coli 
2023-03-11 | PXD034618 | Pride
Biogas upgrade Biological methanation Hydrogen starvation Renewable energy Hydrogenotrophic methanogens Acetoclastic methanogens Power to methane Microbial food-web Metaproteomics 
ProteomicsProteotyping of microbial communities reveals the correlations between the microorganisms and the process parameters
Background: Methane yield and biogas productivity of biogas plants depend on microbial community structure and functionality, substrate supply, and general process parameters. Little is known, however, about the correlations between microbial community function and the process parameters. To close t...
ORGANISM(S): Acyrthosiphon pisum (Pea aphid) 
2016-04-19 | PXD003526 | Pride
Biogas plant Biogas Anaerobic digestion Complex microbial community 
ProteomicsMetaproteomics of fecal samples supports the diagnosis of Crohn’s Disease and Ulcerative Colitis
Objective Crohn’s Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract. Reliable diagnosis of these diseases requires a comprehensive examination of the patient, which include invasive endoscopy. This study assesses whether non-invasive LC-MS/MS ba...
ORGANISM(S): Homo sapiens (Human) 
2019-03-11 | PXD010371 | Pride
• fecal samples • metaproteomics • non-invasive diagnosis • inflammatory bowel disease • crohn’s disease • ulcerative colitis • gastrointestinal tract 
ProteomicsMicrobiome adaptations and the role of abundant metagenomically assembled genomes (MAGs) from a production-scale biogas plant consisting of three independent digesters as revealed by MAG-centric metagenomics and metaproteomics
Current developments have led to a reconsidering of energy policy in many countries with the aim of increasing the share of renewable energies in the energy supply, where the anaerobic digestion (AD) of biomass to produce methane also plays an important role. To improve biomass digestion while ensur...
ORGANISM(S): anaerobic digester metagenome 
2024-01-26 | PXD044571 | Pride
Anaerobic digestion Metagenome analyses Biogas microbiome Metagenomic binning Metaproteome analyses Biogas process chain 
ProteomicsFecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Aims Gut microbiota-mediated inflammation promotes obesity-associated low-grade inflammation, which represents a hallmark of the metabolic syndrome (MetS). Lifestyle-induced weight loss (WL) is regarded as an efficient therapy to reverse MetS and to prevent disease progression. The objective of this...
ORGANISM(S): human gut metagenome 
2021-04-19 | PXD020902 | Pride
Metaproteomics Obesity Metabolic syndrome Microbiome Gut inflammation Weight loss 
ProteomicsGiant panda (Ailuropoda melanoleuca) gut microbiomes degrade bamboo in distinct patterns: heterofermentation of green leaves to ethanol, lactate and acetate, and homofermentation of yellow pith to lactate
The iconic giant panda is an endangered species known worldwide for its peculiar dietary habits. While retaining the digestive system of a carnivore, the giant panda successfully moved into a diet almost exclusively based on bamboo. Digestion of lignocellulose is believed to be conducted solely by i...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Escherichia coli 
2020-03-02 | PXD010872 | Pride
Metaproteomics microbial communities fermentation 
ProteomicsDiscovering biomarkers for non-alcoholic steatohepatitis pa-tients with and without hepatocellular carcinoma using fecal metaproteomics
High-calorie diets lead hepatic steatosis and to the development of non-alcoholic fatty liver disease (NAFLD), which can evolve over many years into the inflammatory form non-alcoholic steatohepatits (NASH) posing a risk for the development of hepatocellular carcinoma (HCC). Due to the diet and the ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD034175 | Pride
Non-alcoholic steatohepatitis Metaproteomics Hepatocellular carcinoma Fecal microbiota Ma-chine learning 
ProteomicsDegradation of C30 - Reduced TCA cycle rates at high hydrostatic pressure hinder hydrocarbon degradation and obligate oil degraders in natural, deep-sea microbial communities
A significant part of the heavier petroleum fraction resulting from offshore oil-spills sinks to the deep-sea. Its fate and biodegradation by microbial communities is unclear. In particular, the physiological and metabolic features of hydrostatic pressure (HP) adapted oil-degraders have been neglect...
ORGANISM(S): Escherichia coli 
2018-12-19 | PXD004328 | Pride
Bioremediation Petroleum Oil Metaproteome Alkane Hydrostatic pressure Deep-sea 
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