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Streptococcus gordonii, an important primary colonizer of dental plaque biofilm, specifically binds to salivary amylase via the surface-associated amylase-binding protein A (AbpA). We hypothesized that amylase binding to S. gordonii modulates expression of chromosomal genes, which could influence ba...
ORGANISM(S): Streptococcus gordonii str. Challis 
We deployed proximity-dependent biotinylation to identify actinin proximity proteins and RNA transcripts in human cardiomyocytes to reveal new functions of the actin cytoskeleton. We identified 285 proximity protein partners including unexpected effectors of RNA-binding and metabolism, and interroga...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD018040 | Pride
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