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ProteomicsSwine flu project - A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture
To investigate the effects of pandemic H1N1 on the host cell proteome
ORGANISM(S): H1N1 subtype 
2012-11-27 | PRD000554 | Pride
ProteomicsMacaque models for influenza A virus
Non-human primates are the animals closest to humans for use in influenza A virus challenge studies, in terms of their phylogenetic relatedness, physiology and immune systems. Previous studies have shown that cynomolgus macaques (Macaca fascicularis) are permissive for infection with H1N1pdm influen...
ORGANISM(S): Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Unidentified Influenza A virus (H1N1) 
2016-06-20 | PXD003803 | Pride
Label free proteomics H1n1pdm influenza virus Intra-nasal challenge 
ProteomicsThe secretome profiling of a pediatric airway epithelium infected with hRSV identified aberrant apical/basolateral trafficking and novel immune modulating (CXCL6, CXCL16, CSF3) and antiviral (CEACAM1) proteins.
The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-25 | PXD013661 | Pride
Cxcl16 Secretome directionality Respiratory syncytial virus Well-differentiated pediatric bronchial epithelial cells (wd-pbecs) Ceacam1 Quantitative proteomics Cxcl6 Csf3 
ProteomicsDetermination of the interactome of Non-Structural Protein12 from Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus with Host Cellular Proteins UsingHigh Throughput Proteomics and Identification of Hsp70 as a Critical Cellular Factor for Virus Biology
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous economic losses and continues to be a serious problem to the swine industry worldwide. Although extensive research has been focused on PRRSV, the structure and function of some viral proteins like nonstructural protein...
ORGANISM(S): Homo sapiens (Human) 
2016-06-27 | PXD004003 | Pride
Label free proteomics Hp-prrsv Nsp12 Hsp70 Inhibitor study Interactome 
ProteomicsSecretome profiling of human airway epithelial cultures infected with respiratory syncytial virus
The respiratory epithelium is a polarised layer at the interface between the outside environment and deeper lung structures, overlaid by the epithelial lining fluid (ELF). This provides a mechanical and immunological barrier to inhaled particulates, such as viruses. Human respiratory syncytial virus...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD004430 | Pride
Human respiratory syncytial virus Human airway epithelial model Secretome Lc-ms/ms 
ProteomicsStage-specific proteomes from Onchocerca ochengi, sister species of the human river blindness parasite, uncovers adaptations to a nodular lifestyle
In spite of 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected. The aetiological agent, Onchocerca volvulus, is a filarial nematode with a complex lifecycle involving several distinct stages in ...
ORGANISM(S): Onchocerca ochengi (Filarial nematode worm) 
2016-05-31 | PXD002889 | Pride
Lc-msms River blindness Onchocerca ochengi 
UnknownCOVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study.
Not available
S-EPMC8231091 | biostudies-literature
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