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ProteomicsIdentification of HJURP binding determinants on the Mis18 complex using photo-cross-linking and mass spectrometry
In the early G1 phase of the cell cycle, human HJURP is recruited to centromeres by the Mis18 complex, which consists of Mis18α, Mis18β and M18BP1. This interaction of HJURP with the Mis18 complex is essential for CENP-A deposition and the preservation of centromere identity. To identify the binding...
ORGANISM(S): Homo sapiens (Human) 
2019-08-01 | PXD013339 | Pride
Photo-cross-linking Q-exactive Abk Human Kinetochore Centromere Protein complex Bpa Stavrox 
GenomicsRNA sequencing of HJURP silencing in ovarian cancer cells
RNA sequencing of HJURP silencing in ovarian cancer cells
PRJNA787567 | ENA
TranscriptomicsRNA sequencing of HJURP silencing in ovarian cancer cells
Ovarian cancer is the most lethal gynecological malignancy. Recurrence and chemoresistance are tough challenges leading to poor prognosis. HJURP is a molecular chaperone of CENP-A, which is associated with aggressive progression in multiple tumors. However, the function of HJURP in ovarian cancer ha...
ORGANISM(S): Homo sapiens 
2022-01-26 | GSE190568 | GEO
UnknownHJURP is involved in the expansion of centromeric chromatin.
Not available
S-EPMC4571335 | biostudies-literature
UnknownHJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma.
Not available
S-EPMC6567799 | biostudies-literature
UnknownInheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP.
Not available
S-EPMC6219920 | biostudies-literature
Genomics
Chromatin remodelling upon HJURP gene silencing
PRJNA855124 | ENA
UnknownHJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
Not available
S-EPMC8771849 | biostudies-literature
UnknownMisregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells.
Not available
S-EPMC3183075 | biostudies-literature
UnknownHJURP modulates cell proliferation and chemoresistance via the MYC/TOP2A transcriptional axis in gastric cancer.
Not available
S-EPMC12021643 | biostudies-literature
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