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GenomicsNew Allele HLA-DRB1
HLA-DRB1*11:04 new
PRJEB64134 | ENA
ProteomicsFucosylation of HLA-DRB1 regulates CD4+T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy: HLA-DRB1 Interactomes
Immunotherapy efficacy is limited in melanoma, and combinations of immunotherapies with other modalities have yielded limited improvements but also adverse events requiring cessation of treatment. In addition to ineffective patient stratification, efficacy is impaired by paucity of intratumoral immu...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD038068 | Pride
Fucosylation Melanoma Interactome Hla-drb1 Immunotherapy 
GenomicsDetection of an HLA-DRB1*14:44
Detection of an HLA-DRB1*14:44
PRJEB35851 | ENA
GenomicsDetection of an HLA-DRB1*16:35
Detection of an HLA-DRB1*16:35
PRJEB35034 | ENA
GenomicsDetection of an HLA-DRB1*04:68
Detection of an HLA-DRB1*04:68
PRJEB35050 | ENA
GenomicsDetection of an HLA-DRB1*14:44
Detection of an HLA-DRB1*14:44
PRJEB35033 | ENA
ProteomicsHLA-DRB1*15:01 and HLA-DRB5*01:01 peptidomes
HLA-DR15 is a haplotype associated with multiple sclerosis. It contains the two DRB* genes DRB1*1501 (DR2b) and DRB5*0101 (DR2a). The reported anchor motif of the corresponding HLA-DR molecules was determined years ago based on a small number of peptide ligands and binding assays. DR2a could display...
ORGANISM(S): Homo sapiens (Human) 
2017-10-10 | PXD006534 | Pride
Hla-dr15 Multiple sclerosis Drb5*0101 Drb1*1501 Hla-ii Peptidome 
GenomicsNew HLA-DRB1*07 allele
New HLA-DRB1*07 allele sequence obtained by Sequence-Based Typing
PRJEB33588 | ENA
GenomicsA new HLA-DRB1*07 allele, identified in a Chinese individual
A new HLA-DRB1*07 allele
PRJEB21367 | ENA
ProteomicsHLA-DRB1 allelic combinations differentially shape dendritic cell antigen presentation enhanced by tumor cell line lysate-pulsing
The study explores the anti-tumor immune response through the analysis of the HLA-II immunopeptidome of dendritic cells (DCs) from HLA-heterozygous donors pulsed with a protein extract from the MCF-7 tumor cell line. The objective was to characterize how different HLA-DRB1 allele combinations influe...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD064999 | Pride
T cell Heterozygosity Mass spectrometry Peptide Dendritic cell Hla-drb1 
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