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UnknownAutoantibodies in Chinese patients with chronic hepatitis B: prevalence and clinical associations.
Not available
S-EPMC4284347 | biostudies-literature
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
ProteomicsProteins bound to BTBD7_hsa_circ_0000563 in coronary artery disease
We aimed to clarify the possible functional role of hsa_circ_0000563 in coronary artery disease. Therefore, the ChIRP-MS was conducted to explore the interaction between BTBD7_hsa_circ_0000563 and proteins on a genomic scale in human peripheral blood mononuclear cell (PBMC). This project is the raw ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033196 | Pride
Chirp-ms Btbd7_hsa_circ_0000563 Proteins Coronary artery disease 
ProteomicsPre-treatment of Interferon-α stimulates DHX58 to prevent hepatic ferroptosis
Characterized by lethal iron accumulation and lipid peroxidation, ferroptosis plays critical roles in liver injury, especially caused by ischemia/reperfusion (I/R) of hepatic inflow occlusion during liver operation. However, the lack of effective and safe clinical precautionary measure is still the ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD042083 | Pride
Interferon  dhx58  gpx4  m6a modification  ythdc2  ferroptosis 
MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
UnknownThe Multi-Omics Architecture of Juvenile Idiopathic Arthritis.
Not available
S-EPMC7602566 | biostudies-literature
ProteomicsRepairing of isoaspartyl residues by PCMT1 alleviates renal fibrosis through the repression of TGF-β1/TGFBR2/Smad signaling pathway
Protein L-isoaspartyl/D-aspartyl Methyltransferase (PCMT1) plays a pivotal role in repairing a spontaneous post-translational modification (PTM) of L-isoaspartyl residues resulted from asparagine deamidation or aspartate isomerization. This PTM is particularly important for extracellular matrix (ECM...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-18 | PXD047057 | Pride
Pcmt1 Tgf-β1-smad pathway Isoaspartyl residues Tgfbr2 Extracellular matrix Renal fibrosis 
UnknownBioinformatics identification of key genes correlating NOD1 and Endoplasmic Reticulum stress in Hepatitis B virus-induced acute liver failure.
Not available
S-EPMC12521598 | biostudies-literature
UnknownIdentification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis.
Not available
S-EPMC9542075 | biostudies-literature
UnknownIn pre-clinical study fetal hypoxia caused autophagy and mitochondrial impairment in ovary granulosa cells mitigated by melatonin supplement.
Not available
S-EPMC11464463 | biostudies-literature
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