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MetabolomicsDiscovery and validation of potential serum biomarkers for heart failure by untargeted metabolomics

Detection of biomarkers was extremely important for the early diagnosis, prognosis and therapy optimization of diseases. The purpose of this study was to investigate the differences in serum metabolites between patients with heart failure (HF) and healthy controls (HC), and to diagnose HF qualita...

2025-07-18 | MTBLS9586 | MetaboLights
ProteomicsDPF3 and SNIP1 IP-MS in 786-O cells
In this project, we performed DPF3 and SNIP1 immunoprecipitation followed by mass spectrometry analysis to identify their interacting partners.
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD033421 | Pride
Dpf3 Snip1 
ProteomicsIdentification of E2f1 interactors during early embryonic development in Xenopus tropicalis
In this project, we performed E2f1 immunoprecipitation followed by mass spectrometry analysis to identify its interacting partners during early embryonic development in Xenopus tropicalis.
ORGANISM(S): Xenopus tropicalis 
2025-12-01 | PXD051084 | Pride
Early embryonic development E2f1 Xenopus tropicalis 
ProteomicsAberrant NAD+ metabolism underlies Zika virus-induced microcephaly
ZIKV-infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. Here, we reveal extensive and large-scale metabolic reprogramming events in ZIKV-infected mouse brains. We perform a multi-omics study comprising transcriptomics, proteomics, ...
ORGANISM(S): Mus Musculus 
2021-06-18 | PXD026814 |
ProteomicsThe inhibition effect of ERAP1-IN-1 on HepG2.2.15 cells
In our strudy, we preterated HepG2.2.15 cells with specific ERAP1 inhibitor ERAP1-IN-1(50μM). And then LC-MS/MS analysis was performed on a timsTOF Pro mass spectrometer.Finally we found that among the total peptides identified, ERAP1-IN-1-treated group had an reduction of the numbers of long pepti...
ORGANISM(S): Homo Sapiens 
2022-02-24 | PXD031858 |
ProteomicsComprehensive mass spectrometry strategy for developing proteomic biomarkers of intracranial aneurysms
This study deals with discovering biomarkers for the diagnosis of intracranial aneurysm
ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens 
2021-07-05 | PXD027116 |
ProteomicsLongitudinal proteomic investigation of COVID-19 vaccination
163 participants with paired peripheral blood mononuclear cells and serum samples，at D0, D28, day 57 (D57) by TMT-based proteomics
ORGANISM(S): Homo Sapiens 
2023-09-06 | PXD039826 |
ProteomicsCirculating proteomic panels for risk stratification of intracranial aneurysm and its rupture
This study deals with discovering biomarkers for the diagnosis of intracranial aneurysm
ORGANISM(S): Homo Sapiens 
PXD024615 |
ProteomicsRaw data of 218 FFPE tissue proteomes containing 144 tissue samples from seven organs of fatal VID-19 cases and 74 control specimens from 56 non-COVID-19 individuals
144 tissue samples from postmortem lung, liver, kidney, heart, spleen, testis and thyroid collected from 19 COVID-19 cases and 74 control specimens from 56 non-COVID-19 individuals were analyzed by PCT and TMT 16-plex based proteomics.
ORGANISM(S): Homo Sapiens 
2020-12-11 | PXD022775 |
ProteomicsArtificial intelligence defines protein-based classification of thyroid nodules
We applied PCT-DIA on a total of 1161 nodules from 1133 patients using either tissue cores (1 mm diameter; 0.5–1 mm depth) punched from regions of interest marked on retrospective FFPE tissue blocks or prospective cytology specimens from FNA aspirates. The samples comprise (i) a discovery set of FFP...
ORGANISM(S): Homo Sapiens 
PXD036554 |
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