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UnknownHuang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Not available
S-EPMC10777866 | biostudies-literature
UnknownHybrid Perovskite-Photovoltaic and Solar-Thermal Harvesting.
Not available
S-EPMC12622551 | biostudies-literature
ProteomicsNatural small molecule DP combats liver fibrosis by targeting APOL2
Liver fibrosis is an urgent clinical problem without effective treatment. Herein, we conducted a high-content screening on a natural “privileged” diterpenoid library to identify a potent anti-liver fibrosis lead DP. Leveraging photoaffinity labeling approach, apolipoprotein L2 (APOL2), an ER-rich pr...
ORGANISM(S): Homo sapiens (Human) 
2024-08-13 | PXD047924 | Pride
Apol2 Anti-liver fibrosis Natural small molecule Er stress Hes1 
ProteomicsA natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2 (APOL2)-mediated endoplasmic reticulum (ER) stress
To investigate the functional role of APOL2 in liver fibrosis, we performed an unbiased immunoprecipitation-mass spectrometry (IP-MS) analysis for APOL2 in the TGF-β1-stimulated LX-2 cell lysates.
ORGANISM(S): Homo sapiens (Human) 
2024-08-13 | PXD047815 | Pride
Apol2 Anti-liver fibrosis Natural small molecule Er stress Hes1 
UnknownDeep-potential enabled multiscale simulation of gallium nitride devices on boron arsenide cooling substrates.
Not available
S-EPMC10963741 | biostudies-literature
ProteomicsTargeting SKAP2-modulated cytoskeleton remodeling restores sperm motility
Our work recognized heterogeneous nuclear ribonucleoprotein R (hnRNPR) is a master regulator of m6A-dependent pre-mRNA splicing. Genetic mutation in HNRNPR leads to asthenoteratozoospermia in both humans and mice, culminating in complete sterility. Mechanistically, genetic ablation of Hnrnpr manifes...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-13 | PXD067981 | Pride
Lc-ms 
UnknownGenetic Characterization of Archived Bunyaviruses and their Potential for Emergence in Australia.
Not available
S-EPMC4861517 | biostudies-literature
UnknownUnveiling precision: a data-driven approach to enhance photoacoustic imaging with sparse data.
Not available
S-EPMC10783920 | biostudies-literature
UnknownRole of SNAP-25 MnlI variant in impaired working memory and brain functions in attention deficit/hyperactivity disorder.
Not available
S-EPMC9575616 | biostudies-literature
UnknownNovel RNA base pair with higher specificity using single selenium atom.
Not available
S-EPMC3367167 | biostudies-literature
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