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ProteomicsHO-1/BMMSCs exosomes treating inflammatory injured IEC-6 cells LC-MSMS
In this study, we established a rat small intestinal cell (IEC-6) injury model with tumor necrosis factor-α (TNF-α). Then, we added the exosomes from TNF- α damaged IEC-6 (TNF-α-exo), co-cultured with BMMSCs exosomes (BM-exo) and heme oxygenase-1 modified BMMSCs (HBM-exo) system exosomes into IEC-6 ...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-06-29 | PXD017002 | Pride
Rat；iec-6s  ho-1；bmmscs；lc-msms 
TranscriptomicsExpression data from Control or ShSuz12 rat Intestinal epithelial cells IEC-6
Polycomb-group proteins form multimeric protein complexes involved in transcriptional silencing. The Polycomb Repressive complex 2 (PRC2) contains the Suppressor of Zeste-12 protein (Suz12) and the histone methyltransferase Enhancer of Zeste protein-2 (Ezh2). This complex, catalyzing the di- and tri...
ORGANISM(S): Rattus norvegicus 
2014-08-02 | E-GEOD-60003 | biostudies-arrayexpress
ProteomicsProteome profiling of IEC-6 cells after treatment with Akkermansia muciniphila (AM), Bifidobacterium longum (BL), or AM-BL combination
To profile the proteome of intestinal epithelial IEC-6 cells in response to treatment with Akkermansia muciniphila, Bifidobacterium longum, or Akkermansia muciniphila + Bifidobacterium longum co-culture. In addition, we also add arabinoxylan (AX) to Akkermansia muciniphila + Bifidobacterium longum c...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-09-24 | PXD061633 | Pride
Iec-6 Akkermansia muciniphila Bifidobacterium longum Co-culture 
GenomicsEffect of deoxynivalenol and acrylamide on gene expression on IEC-6 intestinal cells
Effect of deoxynivalenol and acrylamide on gene expression on IEC-6 intestinal cells
PRJNA1235628 | ENA
TranscriptomicsMurine small intestinal crypt cell line IEC-6: control vs. TGF-beta stimulated
microRNA profiling of rat small intestinal crypt cell IEC-6. Comparing control untreated with cells treated with transforming growth factor-beta (TGF-beta). TGF-beta stimulated cell differentiation, as observed in the stimulation of intestinal epithelial cell markers (alkaline phophotase, villin, am...
ORGANISM(S): Rattus norvegicus 
2012-06-18 | E-GEOD-20982 | biostudies-arrayexpress
ProteomicsPathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury
Intestinal ischemia-reperfusion (IR) injury is initiated when natural IgM antibodies recognize neo-epitopes that are revealed on ischemic cells. The target molecules and mechanisms whereby these neo-epitopes become accessible to recognition are not well understood. Proposing that isolated intestinal...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14862 | biostudies-arrayexpress
UnknownMagnolol pretreatment attenuates heat stress-induced IEC-6 cell injury.
Not available
S-EPMC4913790 | biostudies-literature
TranscriptomicsTranscription profiling of rat intestinal epithelial IEC-6 cells treated with non-steroidal anti-inflammatory agents to investigate gastrointestinal toxicity of NSAIDs
Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively as therapeutic agents, despite their well-documented gastrointestinal (GI) toxicity. Presently, the mechanisms responsible for NSAID-associated GI damage are incompletely understood. In this study, we used Microarray analysis to gen...
ORGANISM(S): Rattus norvegicus 
2009-03-27 | E-GEOD-7584 | biostudies-arrayexpress
UnknownAltered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG.
Not available
S-EPMC2678987 | biostudies-literature
TranscriptomicsEffect of deoxynivalenol and acrylamide on gene expression on IEC-6 intestinal cells
To investigate the effect of co-treatment with deoxynivalenol and acrylamide, rat IEC-6 intestinal cells were treated during four hours with different concentrations of compound alone or together.
ORGANISM(S): Rattus norvegicus 
2026-03-03 | GSE291848 | GEO
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