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ProteomicsIntact N-glycopeptide signatures of immunoglobulin G molecules in plasma from patients with prostate carcinoma and benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH) is difficult to discriminate from prostate carcinoma (PCa) preoperatively. The non-invasive biomarkers are necessary to reduce the burden of biopsies and improve survival quality of patients. Previous research suggests that abnormal glycosylation of immunoglobulin ...
ORGANISM(S): Homo sapiens (Human) 
2020-06-29 | PXD016175 | Pride
Plasma Glycosylation Human Iggs 
ProteomicsLC-MS/MS data for HCA mRNA antibodies
Fc N-glycosylation of IgGs is necessary for effector functions and is a crucial component of quality control. Fc N-glycan profiles of HCA produced by two platforms were determined using mass spectrometry which revealed major differences in site occupancy, glycan types, and glycoform distribution.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD047910 | Pride
Glycosylation Igg Lc-ms/ms 
UnknownNon-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay.
Not available
S-EPMC3113848 | biostudies-literature
UnknownSeptin-5 and -7-IgGs: Neurologic, Serologic, and Pathophysiologic Characteristics.
Not available
S-EPMC9672904 | biostudies-literature
UnknownAntigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria.
Not available
S-EPMC4249335 | biostudies-literature
ProteomicsTowards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS
Advanced analytical strategies including top-down and middle-up HPLC-MS approaches have become powerful alternatives to classical bottom-up analysis for the characterization of therapeutic monoclonal antibodies. Here, we assess feasibility of middle-up analysis of polyclonal IgGs posing additional c...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-26 | PXD014710 | Pride
Speb Phl p 6 vaccination Murine igg subclass quantification N-glycosylation 
UnknownAdvanced analyses of kinetic stabilities of iggs modified by mutations and glycosylation.
Not available
S-EPMC4500310 | biostudies-literature
UnknownBispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs.
Not available
S-EPMC10922565 | biostudies-literature
UnknownDesign Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds.
Not available
S-EPMC6640675 | biostudies-literature
UnknownAutoimmunoreactive IgGs from patients with postural orthostatic tachycardia syndrome.
Not available
S-EPMC3786406 | biostudies-literature
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