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TranscriptomicsTranscription profiling of mouse C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression
Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this s...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8312 | biostudies-arrayexpress
ProteomicsTargeted mass spectrum on activation-state-dependent Integrin alpha 5
Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-10-13 | PXD058550 | Pride
Integrin activation Zebrafish somite Integrin alpha 5 Actin adaptor Integrin actin linker Integrin 
TranscriptomicsTranscription profiling of mouse skeletal muscle of integrin alpha7 overexpressing animals vs controlls
Analysis of integrin alpha7 transgenic mice skeletal muscle transcription profiles comparing to wild type controls. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dyst...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8313 | biostudies-arrayexpress
ProteomicsTargeted mass spectrum on activation-state-dependent Integrin alpha 5
Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio Rerio 
2025-11-10 | PXD058747 | panorama
TranscriptomicsExpression data from 13 week human fetal scalp epidermis sorted for expression of alpha 6 integrin and CD133
CD133 is expressed by a subpopulation of human fetal hair follicle placode cells during early hair development. Its expression, which is gradually lost as the placode matures, correlates with early morphogenesis. We used microarrays to analyze differences in gene expression between alpha-6 integrin+...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-58393 | biostudies-arrayexpress
TranscriptomicsGene expression in b1-integrin wild-type and knockout mouse heart
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14411 | biostudies-arrayexpress
TranscriptomicsCre-mediated deletion of b1 integrin in pancreatic b-cells
In this study, we investigated the function of beta integrins in developing islet beta-cells by targeting the deletion of exon 3 of the B1 integrin gene using a Cre-lox approach. Our results demonstrate that this class of integrin receptors is critically important for proper beta cell expansion duri...
ORGANISM(S): Mus musculus 
2013-07-31 | E-MEXP-3736 | biostudies-arrayexpress
TranscriptomicsAnalysis of human myeloma cell lines expressing beta 3 integrin
The aim of these experiments was designed to compare gene expression in human myeloma cell lines expressing beta 3 integrin vs counterpart cell lines that do not express beta 3 integrin. Keywords: Gene expression,cell lines, siRNA Phenotype characterization of both primary and cultured myeloma plas...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-15867 | biostudies-arrayexpress
TranscriptomicsKlf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated membrane Beta1/Beta2-integrin expression
The Kruppel-like factor 5 (Klf5) regulates pluripotent stem cell self-renewal but its role in somatic stem cells is unknown. Klf5 deficient hematopoietic stem cells and progenitors (HSC/P) fail to engraft after transplantation. This HSC/P defect was associated with impaired bone marrow (BM) homing a...
ORGANISM(S): Mus musculus 
2013-01-30 | E-GEOD-43806 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse epidermal cells sorted into three populations based on alpha 6 integrin, CD34 or Sca-1 surface marker expression
Epidermal keratinocytes were isolated from adult murine skin and FACS sorted into three populations based on their surface maker expression of alpha 6 integrin, CD34 and Sca-1.
- Alpha 6 positive cells constitute the entire population of basal or proliferative keratinocytes from the interfolli...
ORGANISM(S): Mus musculus 
2009-11-16 | E-MEXP-928 | biostudies-arrayexpress
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