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GenomicsInteractome CRISPR screen for rhabdomyosarcoma cells driven by four oncofusions
Interactome CRISPR screen for rhabdomyosarcoma cells driven by four oncofusions
PRJNA1393121 | ENA
TranscriptomicsDetermination of the protein interactome of the transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors
Coordinate expression of the somatic cell reprogramming factors Oct4, Sox2, Klf4 and c-Myc within embryonic stem cells preserves the self-renewal of these cells, while allowing for the expression epitope tagged Sox2. Taking advantage of this observation, we engineered embryonic stem cells (i-OSKM-ES...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-34801 | biostudies-arrayexpress
OtherInteractome CRISPR screen for rhabdomyosarcoma cells driven by four oncofusions
We identified and interactome for seven diffent rhabdomyosarcoma oncofusions. The proliferative effects of the loss of these proteins was tested by a CRISPR loss of function library screen in four rhabdomyosarcoma cell lines engineered to be driven by 4 different oncofusions.
ORGANISM(S): Homo sapiens 
2026-03-26 | GSE314907 | GEO
UnknownComprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding.
Not available
S-EPMC7515726 | biostudies-literature
UnknownDeriving Heterospecific Self-Assembling Protein-Protein Interactions Using a Computational Interactome Screen.
Not available
S-EPMC4751974 | biostudies-literature
ProteomicsRhoGAP/GEF interactome - We performed a systematic study of 141 mammalian RhoGAPs and GEFs including their interactome, specificity and localisation. Here we submit the data from the interactome screen that were processed using MaxQuant.
We performed a systematic study of 141 mammalian RhoGAPs and GEFs including their interactome, specificity and localisation. Here we submit the data from the interactome screen that were processed using MaxQuant.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-01-21 | PXD010084 | Pride
Rho signaling Rhogap Rhogef Interactome 
UnknownProteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.
Not available
S-EPMC1864981 | biostudies-literature
ProteomicsRhoGAP/GEF Interactome - In this project we cloned 141 mammalian RhoGAPs/GEFs (112 human, 26 mouse, 2 rat, 1 chimpanzee) and performed a systematic study of their interactome, localisation and specificity. Here we submit the mass spectrometry data from the interactome screen.
In this project we cloned 141 mammalian RhoGAPs/GEFs (112 human, 26 mouse, 2 rat, 1 chimpanzee) and performed a systematic study of their interactome, localisation and specificity. Here we submit the mass spectrometry data from the interactome screen.
ORGANISM(S): Pan troglodytes (Chimpanzee) Homo sapiens (Human) Mus musculus (Mouse) Rattus norvegicus (Rat) 
2020-01-21 | PXD010144 | Pride
Mammalian Interactome Rhogaps Rho signaling Rhogefs 
ProteomicsA proteomics-based interaction screen links DYRK1A to RNF169 and to the DNA damage response
DYRK1A is a protein kinase whose dysregulation is linked to disease in humans. On the one side, its overexpression in trisomy 21 has been linked to certain Down syndrome pathological traits, while inactivating mutations in just one allele that hinders its function are responsible for a rare clinical...
ORGANISM(S): Homo sapiens (Human) 
2019-07-15 | PXD011925 | Pride
Dyrk1a Rnf169 Dna damage Interactome Lcmsms 
UnknownInfluenza virus-host interactome screen as a platform for antiviral drug development.
Not available
S-EPMC4451456 | biostudies-literature
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