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UnknownCalixarene-mediated assembly of a small antifungal protein.
Not available
S-EPMC6400181 | biostudies-literature
ProteomicsPHD3 and FIH substrates cluster in distinct signalling pathways
Amino acid hydroxylation is a common post-translational modification which regulates intra and inter-molecular protein-protein interactions. The modifications are regulated by a family of 2-oxoglutarate (2OG) dependent enzymes and although the biochemistry is well understood, until now only a few su...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080766 | MassIVE
GenomicStudy of Irish Amyotrophic Lateral Sclerosis (SIALS)

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motor neurons. Epidemiological studies indicate that 2-5% of cases are familial, usually with an autosomal dominant pattern of inheritance. For a portion of these, causative genes have been...

phs000127 | dbGaP
ProteomicsGrowth cone localization of the mRNA encoding a chromatin regulator modulates neurite outgrowth
Neurons exploit local mRNA translation and retrograde transport of transcription factors to regulate gene expression in response to signaling events at distal neuronal ends. Whether epigenetic factors could also be involved in such regulation is not known. We report that the mRNA encoding the HMGN5 ...
ORGANISM(S): Mus musculus (Mouse) 
2015-04-17 | PXD001070 | Pride
Hmgn5 Neuronal development Chromatin regulation 
UnknownPsychological distress and trauma in doctors providing frontline care during the COVID-19 pandemic in the United Kingdom and Ireland: a prospective longitudinal survey cohort study.
Not available
S-EPMC8275363 | biostudies-literature
ProteomicsPHD3 and FIH substrates cluster in distinct signalling pathways
Amino acid hydroxylation is a common post-translational modification which regulates intra and inter-molecular protein-protein interactions. The modifications are regulated by a family of 2-oxoglutarate (2OG) dependent enzymes and although the biochemistry is well understood, until now only a few su...
ORGANISM(S): Homo sapiens (Human) 
2016-03-30 | PXD001085 | Pride
Mapk6 Dmog Ripk4 Erk3 Hypoxia Hydroxylases 
UnknownPsychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland.
Not available
S-EPMC9339913 | biostudies-literature
UnknownNeuroblastoma Invasion Strategies Are Regulated by the Extracellular Matrix.
Not available
S-EPMC7916632 | biostudies-literature
UnknownNeed for recovery amongst emergency physicians in the UK and Ireland: a cross-sectional survey.
Not available
S-EPMC7607596 | biostudies-literature
ProteomicsFIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1.
The asparagine hydroxylase, factor inhibiting HIF (FIH) confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia. Studies investigating whether asparagine hydroxylation is a general regulatory oxygen-dependent modification hav...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080695 | MassIVE
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