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GenomicsChIP-seq of ERα in MCF7 cells treated with the hypoxia mimetic DMOG versus vehicle control
While many studies have investigated the effects of hypoxia on the progression of ER-positive (ER⁺) breast cancer, the impact of hypoxia on estrogen receptor alpha (ERα) signalling remains relatively understudied. In this dataset, we examine how the hypoxia mimetic DMOG influences ERα chromatin bind...
ORGANISM(S): Homo sapiens 
2025-07-21 | E-MTAB-15329 | biostudies-arrayexpress
GenomicsHypoxia and dimethyloxalylglycine (DMOG) downregulates tryptophan-2,3-dioxygenase (TDO2) expression in GBM cells
Hypoxia and dimethyloxalylglycine (DMOG) downregulates tryptophan-2,3-dioxygenase (TDO2) expression in GBM cells
PRJNA576263 | ENA
GenomicsTranscriptome-wide expression changes over time in cultured primary human monocytes due to DMOG treatment
Transcriptome-wide expression changes over time in cultured primary human monocytes due to DMOG treatment
PRJNA698949 | ENA
ProteomicsEnhanced RNA Interactome capture (eRIC) and RNA Interactome capture (RIC) of Jurkat cells (DSMZ, ACC-282) exposed to 0.5mM DMOG or vehicle (DMSO) for 6 hours.
1.0 – 1.3 x 10e8 proliferating Jurkat cells at a density of about 1-1.5 x 10e6 cells/mL were employed per sample. Cells were incubated with 0.5mM DMOG (Cayman Chemical Company, 71210) or an equivalent volume of Dimethyl Sulfoxide (DMSO) (vehicle, Merck 1.02950.0500). The DMSO concentration in the...
ORGANISM(S): Homo sapiens (Human) 
2018-09-03 | PXD010942 | Pride
Dmog Ric Eric N6-methyladenosine Epitranscriptome M6a Rna interactome Rbps Rbpome Rna-binding proteins Dimethyloxalylglycine 
GenomicsGenome-wide chromatin accessibility changes over time in cultured primary human monocytes due to DMOG treatment
Genome-wide chromatin accessibility changes over time in cultured primary human monocytes due to DMOG treatment
PRJNA698950 | ENA
UnknownExploration of metabolic responses towards hypoxia mimetic DMOG in cancer cells by using untargeted metabolomics.
Not available
S-EPMC9460158 | biostudies-literature
GenomicsExpression data from the hepatic stellate cell line LX-2 after treatment with DMOG and from the liver sinusoidal endothelial cell line TRP3 after incubation with conditioned medium of DMOG-treated LX-2
Expression data from the hepatic stellate cell line LX-2 after treatment with DMOG and from the liver sinusoidal endothelial cell line TRP3 after incubation with conditioned medium of DMOG-treated LX-2
PRJNA542810 | ENA
TranscriptomicsTranscriptome-wide expression changes over time in cultured primary human monocytes due to DMOG treatment
RNA sequencing of primary human monocytes cultured with and without hypoxia-mimetic agent DMOG (Dimethyloxalylglycine). Monocytes isolated from PBMCs of 7 healthy donors were cultured with and without DMOG for 24hrs and harvested at 0, 2, 10 or 24hrs for RNA sequencing. DMOG suppresses HIF Prolyl hy...
ORGANISM(S): Homo sapiens 
2022-04-13 | GSE165998 | GEO
GenomicsGenome-wide chromatin accessibility changes over time in cultured primary human monocytes due to DMOG treatment
ATAC sequencing of primary human monocytes cultured with and without hypoxia-mimetic agent DMOG (Dimethyloxalylglycine). Monocytes isolated from PBMCs of 7 healthy donors were cultured with and without DMOG for 24hrs and harvested at 0, 2, 10 or 24hrs for RNA sequencing. DMOG suppresses HIF Prolyl h...
ORGANISM(S): Homo sapiens 
2022-04-13 | GSE165997 | GEO
GenomicsNext-Generation Standard RNA-Sequencing Analysis of human monocytes stimulated by HMGB1 with or without DMOG
Next-Generation Standard RNA-Sequencing Analysis of human monocytes stimulated by HMGB1 with or without DMOG
PRJNA683227 | ENA
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