Iron-recycling - OmicsDI

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Impaired iron recycling from erythrocytes is an early hallmark of aging

Both iron homeostasis and erythropoiesis are known to be affected by aging. Iron needs in mammals are met primarily by iron recycling from senescent red blood cells (RBCs), a task chiefly accomplished by red pulp macrophages (RPMs) in the spleen. Given that RPMs continuously process iron, their cell...

ORGANISM(S): Mus musculus (Mouse)

2023-02-02 | PXD032900 | Pride