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TranscriptomicsThe Prion Protein (PrP) is involved in translation via RNA granule-like mRNPs, a connection which is impaired during neurodegenerative diseases
Cytoplasmic RNA granules have emerged as important elements of posttranscriptional and translational regulation. Stress, germinal and neuronal granules contain RNA-binding proteins capable of self-assembly due to prion-like domains. Hyperassembly mediated by these prion-like domains causes several n...
ORGANISM(S): Mus musculus 
2015-11-01 | E-GEOD-57233 | biostudies-arrayexpress
ProteomicsTime series proteome and phosphoproteome of HOG1 deficient Magnaporthe oryzae osmostress
Investigation of rapid evolutionary adaptation events of Magnaporthe oryzae of HOG1 deficient mutants. Osmosensitive mutants adapt and re-gain osmoregulatory capabilities. Proteomics and phosphoproteomics were analyzed to shed light on the underlying processes.
ORGANISM(S): Cellular Organisms 
2023-04-13 | PXD034481 | JPOST Repository
ProteomicsLC-MS confirmation of alternative YPD1 isoforms from Magnaporthe oryzae
This project aims to understand better the stress response mechanisms of components of the well known High Osmolarity Glycerol two-component regulatory system in the model organism Magnaporthe oryzae. Currently, two putative isoforms of the transfer protein YPD1 (MGG_07173) are described as theoreti...
ORGANISM(S): Pyricularia oryzae 70-15 
2021-09-10 | PXD024832 | Pride
In-gel digest Lc-ms/ms Ypd1 Isoform identification Alternative splicing Magnaporthe oryzae 
ProteomicsComparison of DDA (Orbitrap Exploris 480) and DIA (timsTOF Pro 2) phosphoproteomics
In this experiment, 3 replicate phosphopeptide enrichments using titanium dioxide spin tips (GL Science) of the filamentous fungus Magnaporthe oryzae were measured on a) Orbitrap Exploris 480 in DDA and b) timsTOF Pro 2 in DIA for comparison of model/acquisition type differences.
ORGANISM(S): Cellular Organisms 
2023-04-13 | PXD038605 | JPOST Repository
ProteomicsLens Disulfide crosslink
Low glutathione levels are associated with crystallin oxidation in age-related nuclear cataract (ARNC). To understand the role of cysteine residue oxidation, we used the novel approach of comparing human cataracts with glutathione-depleted LEGSKO mouse lenses for intra- vs. intermolecular disulfide ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2016-07-20 | MSV000079952 | MassIVE
ProteomicsPseudomonas putida strains on glucose, aromatics & mixtures
Growth of Pseudomonas putida KT2440 and mt2 on glucose, coumarate, ferulate, and glucose+coumarate & glucose+ferulate mixtures. Quantitation by diDO-IPTL (Waldbauer et al. Anal Chem 2017).
ORGANISM(S): Pseudomonas Putida Kt2440 (ncbitaxon:160488) Pseudomonas Putida Group (ncbitaxon:136845) 
2023-04-21 | MSV000091772 | MassIVE
ProteomicsRAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing
The RAVER1 protein was proposed to serve as a co-factor in guiding the PTBP-dependent control of alternative splicing (AS). Whether RAVER1 solely acts in concert with PTBPs and how it affects cancer cell fate remained elusive. Here we provide the first comprehensive investigation of RAVER1-contro...
ORGANISM(S): Homo sapiens (Human) 
2024-01-11 | PXD043342 | Pride
Cancer Emt Raver1 Tgfb Microrna Ptbp Alternative splicing Risc 
ProteomicsIdentification/quantitation of human Cystatin C fragments
The data uploaded is related to the identification/quantitation of Cystatin C fragment 95-146 in human hemofiltrate. Also, the mass spectrometry analysis of Cystatin C digested with several proteases is included.
ORGANISM(S): Human 
2020-12-16 | MSV000086609 | MassIVE
TranscriptomicsFrequent driver mutations in histone H3.3 and chromatin remodeling genes in paediatric glioblastoma
Whole exome sequencing identified frequent driver mutations in a series of paediatric glioblastomas We used microarray-based profiling to investigate differences in gene expression according to mutational status of driver genes RNA from 27 primary tumor samples was subject to QC by Agilent BioAnalys...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-GEOD-34824 | biostudies-arrayexpress
UnknownDifferentiating clinically important interstitial lung abnormalities in lung cancer screening.
Not available
S-EPMC12506105 | biostudies-literature
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