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MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownRandomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Not available
S-EPMC5569675 | biostudies-literature
ProteomicsLC-MS by circHIPK3 probe method in human oral submucosal fibroblasts
To identify proteins to which circHIPK3 may bind and participate in the regulation of PDGF-BB-induced biological behavior in oral mucosal FBs, the circHIPK3 probe was designed for RNA pull-down experiment, and the proteins obtained from RNA pull-down were identified by silver staining, mass spectrom...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD062842 | Pride
Human oral submucosal fibroblasts Circhipk3 Lc-ms 
MetabolomicsModulation of liver metabolism and gut microbiota by Alhagi-honey alleviated heat stress-induced liver damage

Alhagi-honey (AH) is a well-established traditional ethnic medicine with advantageous effects against diarrhea and headaches. We aim to explore the preventive effect of AH on liver damage induced by heat stress (HS) and its underlying mechanism. HS models were established by thermostat, and mice ...

2024-09-23 | MTBLS10021 | MetaboLights
TranscriptomicsUAP56 couples piRNA clusters to the perinuclear transposon silencing machinery
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2012-11-28 | E-GEOD-35638 | biostudies-arrayexpress
MetabolomicsComparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study
Background: Autism spectrum disorder (ASD) is defined as a pervasive developmental disorder which is caused by genetic and environmental risk factors. Besides the core behavioral symptoms, accumulated results indicate children with ASD also share some metabolic abnormalities. Objectives:
2022-03-02 | MTBLS2421 | MetaboLights
TranscriptomicsUAP56 couples piRNA clusters to the perinuclear transposon silencing machinery [RNA-Seq and RIP-Seq]
The transposon silencing piRNAs are produced from precursors that are encoded by heterochromatic clusters and processed in the perinuclear nuage. We show that the Drosophila nuclear DEAD box protein UAP56, previously implicated in mRNA splicing and nuclear export, co-localizes with the cluster-assoc...
ORGANISM(S): Drosophila melanogaster 
2012-11-28 | E-GEOD-35637 | biostudies-arrayexpress
ProteomicsThe VIR-associated proteins were identified by LC-MS/MS
7-day-old Col-0 seedlings were collected, and 2 g of tissue was ground to a fine powder in liquid nitrogen and homogenized in 2 ml of lysis buffer (50 mM Tris-HCl, pH 7.4, 2.5 mM MgCl2, 100 mM KCl, 0.1% [v/v] Nonidet P-40, 1 μg/ml leupeptin, 1 μg/ml aprotonin, 0.5 mM phenylmethylsulfonyl fluoride, o...
ORGANISM(S): Arabidopsis Thaliana 
2022-11-14 | PXD038080 |
MetabolomicsMetabolomics analyses of cancer tissue from patients with colorectal cancer.
The alteration of metabolism is essential for the initiation and progression of numerous types of cancer, including colorectal cancer (CRC). Metabolomics has been used to study CRC. At present, the reprogramming of the metabolism in CRC remains to be fully elucidated. In the present study, comprehen...
2024-02-08 | MTBLS8090 | MetaboLights
ProteomicsLC-MS/MS analysis of S100A1-interacting proteins
Immune checkpoint blockade (ICB) has revolutionized cancer treatment, but the therapeutic response is highly heterogeneous. A potential mode of resistance is tumor-intrinsic mechanisms leading to an immunosuppressive tumor microenvironment. However, the underlying interactive network remains elusive...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD059275 | Pride
Lc-ms/ms Mouse S100a1 Tumor 
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