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ProteomicsKaryopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage
Nuclear pore complexes (NPCs) discriminate non-specific macromolecules from importin and exportin receptors, collectively termed karyopherins (Kaps), that mediate nucleocytoplasmic transport. This selective barrier function is attributed to the behavior of intrinsically disordered phenylalanine-glyc...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-01-26 | PXD028074 | Pride
Karyopherin Lc-ms Mdck Prm Ibaq Npc 
ProteomicsLabel-Free Quantitative Proteomics Data for NPC Permeability Barrier Dynamics
This dataset contains label-free quantitative (LFQ) mass spectrometry analyses of proteins associated with affinity-purified isolated native Saccharomyces cerevisiae nuclear pore complexes (NPCs). The study compared wild type NPCs (+CP WT NPCs) with NPCs frozen at -80°C, or incubate in buffer at 4°C...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-10-06 | PXD069104 | Pride
Npc Central transporter Lfq 
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UnknownKaryopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage.
Not available
S-EPMC8932525 | biostudies-literature
UnknownKaryopherins regulate nuclear pore complex barrier and transport function.
Not available
S-EPMC5674887 | biostudies-literature
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