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Unknown1015. Gastrointestinal (GI) Adverse Events With Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Through Week 96: An AMBER Post Hoc Analysis
Not available
S-EPMC7776806 | biostudies-literature
ProteomicsIdentification of peptide isoforms in gS-crystallin using stable isotope labeled peptides
ɣS-crystallin is a major protein of the human lens and is highly modified with age and cataract due to a lack of lens protein turnover. Previous studies have identified some sites of isomerization and racemization of deamidated asparaginyl and aspartyl residues in ɣS but have been limited due to the...
ORGANISM(S): Homo Sapiens 
PXD063350 | panorama
ProteomicsIdentification of novel pyrazolopyrimidine compounds that modulate the shelterin complex and telomere length regulation via phosphoglycerate kinase 1 and stress sensor DJ1
Telomere signalling and metabolic dysfunction are hallmarks of cell aging, and are associated with a variety of pathologies. Identification of new agents targeting these processes might provide therapeutic opportunities, including chemoprevention strategies against cancer predisposition. Here we rep...
ORGANISM(S): Homo sapiens (Human) 
2019-07-19 | PXD011356 | Pride
Trf2 Shelterin Dj1 Pgk1 Telomere Stress 
UnknownA Novel Application of Spectrograms with Machine Learning Can Detect Patient Ventilator Dyssynchrony.
Not available
S-EPMC10426752 | biostudies-literature
TranscriptomicsRNA-seq analysis of alternative splicing events in duplicated genes of Arabidopsis thaliana indicates considerable qualitative and quantitative divergence
Divergence of alternative splicing in duplicated genes is investigated Three replicates of RNA-seq for Arabidopsis first true leaf tissue
ORGANISM(S): Arabidopsis thaliana 
2014-09-30 | E-GEOD-57579 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal human melanocytes and melanoma cell lines from advanced lesions
Affymetrix oligonucleotide microarrays were used to assess global differential gene expression comparing normal human melanocytes with six independent melanoma cell strains from advanced lesions. The data, validated at the protein level for selected genes, confirmed the overexpression in melanoma ce...
ORGANISM(S): Homo sapiens 
2007-06-22 | E-GEOD-4570 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanomas to assess metastatic potential defined by specific gene expression profiles with no BRAF signature
The molecular biology of metastatic potential in melanoma has been studied many times previously and changes in the expression of many genes have been linked to metastatic behaviour. What is lacking is a systematic characterization of the regulatory relationships between genes whose expression is re...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4840 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanomas to determine metastatic potential defined by specific gene expression profiles with no BRAF signature.
The molecular biology of metastatic potential in melanoma has been studied many times previously and changes in the expression of many genes have been linked to metastatic behaviour. What is lacking is a systematic characterization of the regulatory relationships between genes whose expression is re...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4845 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanomas to identify metastatic potential defined by specific gene expression profiles with no BRAF signature
The molecular biology of metastatic potential in melanoma has been studied many times previously and changes in the expression of many genes have been linked to metastatic behaviour. What is lacking is a systematic characterization of the regulatory relationships between genes whose expression is re...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4841 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanomas to assess metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature (Mannheim).
The molecular biology of metastatic potential in melanoma has been studied many times previously and changes in the expression of many genes have been linked to metastatic behaviour. What is lacking is a systematic characterization of the regulatory relationships between genes whose expression is re...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4843 | biostudies-arrayexpress
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