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ProteomicsMapping the Proteoform Landscape of Five Human Tissues
Untargeted top-down LC-MS and CZE-MS of five human tissues (kidney, lung, spleen, small intestine, and heart)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-14 | MSV000088565 | MassIVE
ProteomicsSingle Cell Proteoform Analysis Using scPiMS
We introduce single-cell Proteoform imaging Mass Spectrometry (scPiMS), which realizes the benefit of direct solvent extraction and MS detection of intact proteins from single cells drop casted onto glass slides. Sampling and detection of whole proteoforms by individual ion mass spectrometry enables...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-02 | MSV000093994 | MassIVE
Proteomicsp65-HaloTag copurifying proteins in human 293T cells
In effort to develop methodology for targeted top down mass spectrometry of NF kappa B p65 from human cells, we evaluated the utility of HaloTag for purification and analysis of recombinant protein. During our study, two datasets of bottom up LC-MS/MS were generated: one from in-gel digestion of the...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD001932 | Pride
Rela 293t Human Nf kappa b P65 
MetabolomicsGNPS - Fungal Metabologenomics 110 Strains
This dataset includes .mzXML MS profiles for 110 fungal strains each grown on 3 media conditions for used for integrated metabologenomics analysis. Data were collected on a Q Exactive mass spectrometer. Solvent blanks, media blanks, and technical replicates for a subset of strains are also included.
ORGANISM(S): Fungi (ncbitaxon:4751) Aspergillus (ncbitaxon:5052) Ascomycota (ncbitaxon:4890) Penicillium (ncbitaxon:5073) 
2022-07-07 | MSV000089848 | GNPS
ProteomicsDefining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding
NSD2 is a histone methyltransferase that specifically dimethylates histone H3 lysine 36 (H3K36me2), a modification associated with gene activation. Dramatic overexpression of NSD2 in t(4;14) multiple myeloma (MM) and an activating mutation of NSD2 discovered in acute lymphoblastic leukemia (ALL) are...
ORGANISM(S): Homo sapiens (Human) 
2019-06-27 | PXD013759 | Pride
Interacting partners Label-free proteomics Nsd2 Bioid Multiple myeloma Lc-ms/ms 
ProteomicsData for the Blood Proteoform Atlas:DS-07:Natural Killer:Purchased from SCT
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026129 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-63:Neutrophils:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026166 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-64:B Cell:Purchased from STC
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026167 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-65:T-cell CD4:Purchased from STC
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026168 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-29:B Cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026140 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
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