Sort   by:  
 Page size 
ProteomicsEssential role of translation factor eIF5a in cytokine and cell cycle regulation in primary mouse CD8 T lymphocyte
Translation of specific mRNAs is tightly regulated in primary T cells to ensure correct timing and precise delivery of protein syntheses in response to environmental cues. Translation factor eIF5a is known to be important for protein synthesis and is expected to regulate translation of certain diffi...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-11 | PXD021063 | Pride
Cytokine Lymphocyte Hypusine Proliferation Eif5a 
ProteomicsCD8 T lymphocytes deploy embryonic cell cycle control mechanisms for rapid cell proliferation
Rapid proliferation of CD8 T cells is crucial for adaptive immunity against viral infection. CD8 T cells can complete division cycles in less than 6 hours, representing a physiological extreme for somatic mammalian cells. Embryonic stem cells utilize specialized cell cycle control mechanisms, includ...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD077442 | Pride
Proteomics Mouse cell lines Dia Primary cells 
ProteomicsSCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56
Meiosis creates genetic diversity by recombination and segregation of chromosomes. The synaptonemal complex assembles during meiotic prophase I and assists faithful exchanges between homologous chromosomes, but how its assembly/disassembly is regulated remains to be understood. Here we report how ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-12-07 | PXD022755 | Pride
Drosophila 
ProteomicsLow cell number proteomic analysis using in-cell protease digests reveals a robust signature for cell cycle state classification
Comprehensive proteome analysis of rare cell phenotypes remains a significant challenge. We report a method for low cell number mass spectrometry (MS)-based proteomics using protease digestion of mildly formaldehyde-fixed cells in cellulo, which we call the ‘in-cell digest’. We combined this with AM...
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD028117 | Pride
Tk6 In-cell digest Ampl Cell cycle Human 
UnknownCD8 T lymphocytes deploy embryonic cell cycle control mechanisms for rapid cell proliferation
Not available
S-SCDT-10_1038-S44319-026-00830-4 | biostudies-other
UnknownMoorean tree snail survival revisited: a multi-island genealogical perspective.
Not available
S-EPMC3087522 | biostudies-literature
ProteomicsJin_Context_dependent_interactions_between_HSP90_and_kinase_clientele
This submission consists of the mass spectrometry raw files for the manuscript by Jin et al. (Mutational analysis of GSK3B protein kinase together with kinome-wide binding and stability studies suggest context-dependent recognition of kinases by the chaperone HSP90). This submission contains files f...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-01-06 | MSV000079445 | MassIVE
Proteomics2H-Thiopyran-2-Thione Sulfine, a Compound For Converting H2S to HSOH/H2S2 and Increasing Intracellular Sulfane Sulfur Levels
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of suitable donors to produce these species. Herein...
ORGANISM(S): Oryctolagus Cuniculus (ncbitaxon:9986) 
2024-02-07 | MSV000094034 | MassIVE
ProteomicsSo_Kinase_Networks_in_TRAIL_induced_apoptosis
This submission consists of the mass spectrometry raw files for the manuscript by So et al. (Kinase Networks in TRAIL induced apoptosis). This submission contains files for the data presented as supplementary tables 5 (interaction network of 104 protein kinases in DLD-1 cells) acquired on a QSTAR E...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-09 | MSV000078989 | MassIVE
UnknownVariation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study.
Not available
S-EPMC6407836 | biostudies-literature
Sort   by:  
 Page size