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ProteomicsProteomics of Asrij perturbed Drosophila lymph glands as a resource for identification of new regulators of hematopoiesis
Hematological disorders result in perturbed homeostasis of the blood system. However, a comprehensive understanding of how physiological and genetic mechanisms regulate blood cell precursor maintenance and differentiation is lacking. Owing to simplicity and ease of genetic analysis, the Drosophila m...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-05-15 | PXD010753 | Pride
Lymph gland Asrij Differential regulation Escrt Drosophila hematopoiesis Proteome 
ProteomicsPfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum
Calcium Dependent Protein Kinases (CDPKs) are key effectors of calcium signaling in malaria parasite. We have elucidated a novel role of PfCDPK1, which is indispensable for the erythrocytic development of Plasmodium falciparum, in invasion of host Red Blood Cells (RBCs). To gain insights into the m...
ORGANISM(S): Plasmodium falciparum 
2017-05-02 | PXD005207 | Pride
Orbitrap fusion Phosphoproteome 
ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
ProteomicsCharacterization of human pineal gland proteome
Pineal gland is a neuroendocrine gland located at the center of the brain. It protects the body from the effect of toxic compounds and regulates sleep-wake cycle, body temperature and sexual maturity through the secretion of melatonin. Abnormal functioning of pineal glands is known to be associat...
ORGANISM(S): Homo sapiens (Human) 
2017-02-02 | PXD004332 | Pride
Human Gland Tissue Pineal Lc-ms/ms 
ProteomicsProteogenomics of Candida tropicalis – an opportunistic pathogen
Candida tropicalis is an opportunistic pathogen which causes candidiasis in immune-compromised individuals. It is one of the members of the non-albicans group of Candida that are known to be azole resistant and is frequently seen in individuals being treated for cancers, HIV-infection and bone-marr...
ORGANISM(S): Candida tropicalis (Yeast) 
2017-05-08 | PXD001071 | Pride
Genome annotation Shotgun proteomics 
ProteomicsAn Integrated OMICs Approach of Assembly and Annotation of Indian Sandalwood (Santalum album L.) plant genome provides insights into an array of genes involved in Santalol biosynthesis
Indian sandalwood (Santalum album) is an economically important plant known for its aromatic wood. This highly valued plant has also been reported as an endangered species. Despite its economic value, the genome sequence of this plant is not yet available. In the current study,we report the draft ge...
ORGANISM(S): Santalum album 
2019-05-29 | PXD006283 | Pride
Santalum album 
ProteomicsProteomics approaches for decoding Plasmodium yoelii biology
Plasmodium yoelii is a rodent parasite commonly used as a model to study liver-stage development in host system during malaria infection. Mass spectrometry-based proteomics approaches helps in understanding the proteomic profiling of parasite and provided opportunities to explore the mechanisms cont...
ORGANISM(S): Plasmodium yoelii yoelii 17XNL Mus musculus (Mouse) 
2022-04-01 | PXD013932 | Pride
Proteomics Post-translational modifications Plasmodium yoelii 
ProteomicsPhosphoproteomic studies to identify targets and substrates of Protein kinase PfPK2 in human malaria parasite Plasmodium falciparum
The purpose of this project was to identify targets and substrates of Protein kinase PfPK2 in malaria parasite P. falciparum. These studies will help understand the mechanisms via which PfPK2, which is indispensable for the parasite survival, regulates parasite development. For this purpose, PfPK2-...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-10-18 | PXD042264 | Pride
Phosphoproteomics Lasmodium falciparum Tmt Invasion Orbitrap fusion 
ProteomicsNeuroproteomics with Systems Biology: The proteomic landscape of adult human hypothalamus
The hypothalamus is an anatomically small, but functionally crucial region of the human brain. Normal hypothalamus functioning is central to the regulation of neuroendocrine and neurovegetative systems as well as modulation of chronobiology and behavioral aspects of the human body. Till date the hum...
ORGANISM(S): Homo sapiens (Human) 
2021-11-01 | PXD026879 | Pride
Hypothalamus Autophagy Proteomics Proteogenomics Post translational modifications Neuropeptides. Human brain Adult neurogenesis Orbitrap fusion 
ProteomicsData-dependent acquisition based proteomic analysis of Mycobacterium fortuitum ATCC 6841
Detection of species-specific proteotypic peptides for accurate and easy characterization of infectious non-tuberculous mycobacteria such as Mycobacterium fortuitum is essential. Therefore, we carried out an in-depth global proteomic experiment using M. fortuitum ATCC 6841 strain followed by a prote...
ORGANISM(S): Mycolicibacterium fortuitum subsp. fortuitum DSM 46621 = ATCC 6841 Bacteria 
2024-03-07 | PXD040567 | Pride
Mycobacterium fortuitum Non-tuberculous mycobacteria Dda Lc-ms/ms 
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