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TranscriptomicsNeuropeptides:developmental signals in placode progenitor formation
Few families of signaling factors have been implicated in the control of development. Here we identify the neuropeptides nociceptin and somatostatin, a neurotransmitter and neuroendocrine hormone, as a class of developmental signals in chick and zebrafish. We show that signals from the anterior mese...
ORGANISM(S): Gallus gallus 
2014-04-25 | E-GEOD-48116 | biostudies-arrayexpress
ProteomicsHyPep: An Open-Source Software for Identification and Discovery of Neuropeptides using Sequence Homology Searching
Neuropeptides are a class of endogenous peptides that have key regulatory roles in biochemical, physiological, and behavioral processes. Mass spectrometry analyses of neuropeptides often rely on protein informatics tools for database searching and peptide identification. As neuropeptide databases ar...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-02-02 | PXD037058 | Pride
Peptidomics Hypep Homology Mass spectrometry Peptide De novo sequencing Fdr Neuropeptide 
ProteomicsDefinitive Screening Design to Improve Data-Independent MS Analysis of Neuropeptides
A definitive screening design was used to systematically optimize a DIA workflow for crustacean neuropeptide quantitation. We were able to assess several parameters for their effect on increasing quantifiable neuropeptides and predict the optimal value for these parameters.
ORGANISM(S): Callinectes sapidus 
2023-05-10 | PXD038520 | Pride
Design of experiments Neuropeptides Label-free quantitation Library-free 
ProteomicsA Temporal Study of the Perturbation of Crustacean Neuropeptides Due to Severe Hypoxia Using 4-Plex Reductive Dimethylation
Hypoxia (i.e., low oxygen (O2) levels) is a common environmental challenge for several aquatic species, including fish and invertebrates. To survive or escape these conditions, these animals have developed novel biological mechanisms, some regulated by neuropeptides. By utilizing mass spectrometry, ...
ORGANISM(S): Callinectes sapidus 
2020-03-05 | PXD014688 | Pride
Lc-ms Isotopic labeling Neuropeptides Maldi Hypoxia 
ProteomicsEnrichment and Fragmentation Approaches for Enhanced Detection and Characterization of Endogenous Glycosylated Neuropeptides
Glycosylation, a common and heterogeneous post-translational modification plays a key role in altering biomolecule function and other properties. Prior to monitoring regulatory roles, basal glyconeuropeptide expression must be determined. Characterization is partially limited by the lower abundance ...
ORGANISM(S): Callinectes sapidus 
2022-08-19 | PXD033226 | Pride
Glycosylation Neuropeptides Endogenous peptides Mass spectrometry De novo sequencing 
ProteomicsGenomics- and Peptidomics-Based Discovery of Conserved and Novel Neuropeptides in the American Cockroach
As a model hemimetabolous insect species and an invasive urban pest that is globally distributed, the American cockroach, Periplaneta americana, is of great interest in both basic and applied research. Previous studies on P. americana neuropeptide identification have been based on biochemical isolat...
ORGANISM(S): Periplaneta americana 
2020-11-12 | PXD021660 | Pride
Periplaneta americana Genomics Neuropeptides Lcms Peptidomics 
GenomicsEffect of nociceptive neuropeptides on dendritic cells
Effect of nociceptive neuropeptides on dendritic cells
PRJNA899116 | ENA
ProteomicsSignature-Ion Triggered Mass Spectrometry Approach Enabled Discovery of N- and O-linked Glycosylated Neuropeptides in the Crustacean Nervous System
Discovery of N-linked and O-linked glycosylation on crustacean neuropeptides.
ORGANISM(S): Callinectes sapidus Cancer irroratus 
2021-09-08 | PXD014269 | Pride
Crustacean nervous system Ethcd Neuropeptide Glycosylation Lc-ms/ms 
ProteomicsMass spectrometry-driven discovery of neuropeptides mediating nictation behavior of nematodes
Very little is known about the genetic modulation of nictation, a host-finding strategy used by infective juveniles of many pathogenic nematodes, as well as a phoretic strategy of Caenorhabditis elegans dauers. We here use a mass spectrometry-driven approach to find neuropeptides involved in the mod...
ORGANISM(S): Steinernema carpocapsae 
2022-12-08 | PXD034629 | Pride
Nictation Data-dependent acquisition Steinernema carpocapsae Peptidomics Parallel reaction monitoring Caenorhabditis elegans 
ProteomicsNeuropeptides in Lineus longissimus larvae
The goal of this project was to identify potential neuropeptides in extracts from larvae of the nemertean species Lineus longissimus.
ORGANISM(S): Lineus longissimus 
2022-02-16 | PXD023147 | Pride
Larva Neuropeptides Nemertea 
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